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Botox Therapy for Hypertrophy of the Masseter Muscle Causes a Compensatory Increase of Stiffness of Other Muscles of Masticatory Apparatus

Little is known about the nature of masseter muscle hypertrophy. We investigated the masseter muscle stiffness change after a single intra-masseteric session of Botox injections in people with benign bilateral masseter hypertrophy and the effect of the treatment on the stiffness of the temporalis mu...

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Autores principales: Mierzwa, Dorota, Olchowy, Cyprian, Olchowy, Anna, Nawrot-Hadzik, Izabela, Dąbrowski, Paweł, Chobotow, Sławomir, Grzech-Leśniak, Kinga, Kubasiewicz-Ross, Paweł, Dominiak, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225551/
https://www.ncbi.nlm.nih.gov/pubmed/35743871
http://dx.doi.org/10.3390/life12060840
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author Mierzwa, Dorota
Olchowy, Cyprian
Olchowy, Anna
Nawrot-Hadzik, Izabela
Dąbrowski, Paweł
Chobotow, Sławomir
Grzech-Leśniak, Kinga
Kubasiewicz-Ross, Paweł
Dominiak, Marzena
author_facet Mierzwa, Dorota
Olchowy, Cyprian
Olchowy, Anna
Nawrot-Hadzik, Izabela
Dąbrowski, Paweł
Chobotow, Sławomir
Grzech-Leśniak, Kinga
Kubasiewicz-Ross, Paweł
Dominiak, Marzena
author_sort Mierzwa, Dorota
collection PubMed
description Little is known about the nature of masseter muscle hypertrophy. We investigated the masseter muscle stiffness change after a single intra-masseteric session of Botox injections in people with benign bilateral masseter hypertrophy and the effect of the treatment on the stiffness of the temporalis muscle. Stiffness of the muscles was measured with shear-wave elastography at baseline and 3 weeks after Botox injections in 22 otherwise healthy people. Before the treatment, the stiffness of the masseter was lower than of the temporalis muscle (10.18 ± 1.67 kPa vs. 11.59 ± 1.54 kPa; p = 0.002). After the treatment, this difference increased (6.38 ± 1.34 vs. 13.10 ± 1.92; p < 0.0001). The drop in the stiffness of the masseter muscle was symmetrical (left side by 3.78 kPa; right side by 3.83 kPa). No differences between the left and right sides of the face in terms of muscle stiffness were observed. The study shows that Botox injections reduce stiffness of the masticatory muscles which, in turn, increases the stiffness of the temporalis muscles. Due to the knock-on effect of the change in the masseter function on the other masticatory muscles, simultaneous evaluation and treatment of the temporalis muscle may be required to ensure the desired functional and cosmetic effect.
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spelling pubmed-92255512022-06-24 Botox Therapy for Hypertrophy of the Masseter Muscle Causes a Compensatory Increase of Stiffness of Other Muscles of Masticatory Apparatus Mierzwa, Dorota Olchowy, Cyprian Olchowy, Anna Nawrot-Hadzik, Izabela Dąbrowski, Paweł Chobotow, Sławomir Grzech-Leśniak, Kinga Kubasiewicz-Ross, Paweł Dominiak, Marzena Life (Basel) Article Little is known about the nature of masseter muscle hypertrophy. We investigated the masseter muscle stiffness change after a single intra-masseteric session of Botox injections in people with benign bilateral masseter hypertrophy and the effect of the treatment on the stiffness of the temporalis muscle. Stiffness of the muscles was measured with shear-wave elastography at baseline and 3 weeks after Botox injections in 22 otherwise healthy people. Before the treatment, the stiffness of the masseter was lower than of the temporalis muscle (10.18 ± 1.67 kPa vs. 11.59 ± 1.54 kPa; p = 0.002). After the treatment, this difference increased (6.38 ± 1.34 vs. 13.10 ± 1.92; p < 0.0001). The drop in the stiffness of the masseter muscle was symmetrical (left side by 3.78 kPa; right side by 3.83 kPa). No differences between the left and right sides of the face in terms of muscle stiffness were observed. The study shows that Botox injections reduce stiffness of the masticatory muscles which, in turn, increases the stiffness of the temporalis muscles. Due to the knock-on effect of the change in the masseter function on the other masticatory muscles, simultaneous evaluation and treatment of the temporalis muscle may be required to ensure the desired functional and cosmetic effect. MDPI 2022-06-06 /pmc/articles/PMC9225551/ /pubmed/35743871 http://dx.doi.org/10.3390/life12060840 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mierzwa, Dorota
Olchowy, Cyprian
Olchowy, Anna
Nawrot-Hadzik, Izabela
Dąbrowski, Paweł
Chobotow, Sławomir
Grzech-Leśniak, Kinga
Kubasiewicz-Ross, Paweł
Dominiak, Marzena
Botox Therapy for Hypertrophy of the Masseter Muscle Causes a Compensatory Increase of Stiffness of Other Muscles of Masticatory Apparatus
title Botox Therapy for Hypertrophy of the Masseter Muscle Causes a Compensatory Increase of Stiffness of Other Muscles of Masticatory Apparatus
title_full Botox Therapy for Hypertrophy of the Masseter Muscle Causes a Compensatory Increase of Stiffness of Other Muscles of Masticatory Apparatus
title_fullStr Botox Therapy for Hypertrophy of the Masseter Muscle Causes a Compensatory Increase of Stiffness of Other Muscles of Masticatory Apparatus
title_full_unstemmed Botox Therapy for Hypertrophy of the Masseter Muscle Causes a Compensatory Increase of Stiffness of Other Muscles of Masticatory Apparatus
title_short Botox Therapy for Hypertrophy of the Masseter Muscle Causes a Compensatory Increase of Stiffness of Other Muscles of Masticatory Apparatus
title_sort botox therapy for hypertrophy of the masseter muscle causes a compensatory increase of stiffness of other muscles of masticatory apparatus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225551/
https://www.ncbi.nlm.nih.gov/pubmed/35743871
http://dx.doi.org/10.3390/life12060840
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