Immune suppressive function of IL-1α release in the tumor microenvironment regulated by calpain 1

Interleukin-1α (IL-1α) plays an important role in inflammation and hematopoiesis. Many tumors have increased IL-1α expression. However, the immune regulatory role of secreted IL-1α in tumor development and whether it can be targeted for cancer therapy are still unclear. Here, we found that tumoral-s...

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Detalles Bibliográficos
Autores principales: Lin, Dandan, Mei, Yu, Lei, Lei, Binte Hanafi, Zuhairah, Jin, Ziqi, Liu, Yonghao, Song, Yuan, Zhang, Yinsheng, Hu, Bo, Liu, Chunliang, Lu, Jinhua, Liu, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225674/
https://www.ncbi.nlm.nih.gov/pubmed/35756844
http://dx.doi.org/10.1080/2162402X.2022.2088467

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