Inhibition of Streptococcus mutans adhesion and biofilm formation with small-molecule inhibitors of sortase A from Juniperus chinensis

BACKGROUND: Streptococcus mutans, an important Gram-positive pathogen in dental caries, uses sortase A (SrtA) to anchor surface proteins to the bacterial cell wall, thereby promoting biofilm formation and attachment to the tooth surface. DESIGN: Based on activity-guided separation, inhibitors of S....

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Detalles Bibliográficos
Autores principales: Cho, Eunji, Hwang, Ji-Yeon, Park, Jae Sung, Oh, Daehyun, Oh, Dong-Chan, Park, Hyeung-Geun, Shin, Jongheon, Oh, Ki-Bong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225741/
https://www.ncbi.nlm.nih.gov/pubmed/35756538
http://dx.doi.org/10.1080/20002297.2022.2088937

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