Cargando…

Improvement of two Mn(2+) coordination polymers on cognitive function of aged rats after anesthesia

Two Mn(2+) coordination polymers (CPs) with the scientific terms of {[Mn(TTPA)·(H(2)O)(2)]·H(2)O}(n) (1) and {[Mn(TTPA)·(H(2)TTPA)]·2DMSO}(n) (2) were favorably created on the basis of multidentate linking organic ligand 2,5-bis-(1,2,4-triazol-1-yl)-terephthalic acid (H(2)TTPA) in the conditions of...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Hao-Lin, Jia, Qiang, Tian, Fen, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225759/
https://www.ncbi.nlm.nih.gov/pubmed/35755881
http://dx.doi.org/10.1080/15685551.2022.2090678
_version_ 1784733691645263872
author Zhang, Hao-Lin
Jia, Qiang
Tian, Fen
Zhang, Hui
author_facet Zhang, Hao-Lin
Jia, Qiang
Tian, Fen
Zhang, Hui
author_sort Zhang, Hao-Lin
collection PubMed
description Two Mn(2+) coordination polymers (CPs) with the scientific terms of {[Mn(TTPA)·(H(2)O)(2)]·H(2)O}(n) (1) and {[Mn(TTPA)·(H(2)TTPA)]·2DMSO}(n) (2) were favorably created on the basis of multidentate linking organic ligand 2,5-bis-(1,2,4-triazol-1-yl)-terephthalic acid (H(2)TTPA) in the conditions of solvent-presupposed thermal reaction. To measure the influence of two Mn(2+) coordination polymers with novel structures, the ELISA assay and real-time RT-PCR assay were conducted in this present research. First of all, the ELISA assay was conducted to measure the content of inflammatory cytokines released into the hippocampal tissue. In addition to this, the relative expression of the TAU protein in the brain was further determined with real-time RT-PCR assay.
format Online
Article
Text
id pubmed-9225759
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Taylor & Francis
record_format MEDLINE/PubMed
spelling pubmed-92257592022-06-24 Improvement of two Mn(2+) coordination polymers on cognitive function of aged rats after anesthesia Zhang, Hao-Lin Jia, Qiang Tian, Fen Zhang, Hui Des Monomers Polym Full Length Article Two Mn(2+) coordination polymers (CPs) with the scientific terms of {[Mn(TTPA)·(H(2)O)(2)]·H(2)O}(n) (1) and {[Mn(TTPA)·(H(2)TTPA)]·2DMSO}(n) (2) were favorably created on the basis of multidentate linking organic ligand 2,5-bis-(1,2,4-triazol-1-yl)-terephthalic acid (H(2)TTPA) in the conditions of solvent-presupposed thermal reaction. To measure the influence of two Mn(2+) coordination polymers with novel structures, the ELISA assay and real-time RT-PCR assay were conducted in this present research. First of all, the ELISA assay was conducted to measure the content of inflammatory cytokines released into the hippocampal tissue. In addition to this, the relative expression of the TAU protein in the brain was further determined with real-time RT-PCR assay. Taylor & Francis 2022-06-20 /pmc/articles/PMC9225759/ /pubmed/35755881 http://dx.doi.org/10.1080/15685551.2022.2090678 Text en © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Full Length Article
Zhang, Hao-Lin
Jia, Qiang
Tian, Fen
Zhang, Hui
Improvement of two Mn(2+) coordination polymers on cognitive function of aged rats after anesthesia
title Improvement of two Mn(2+) coordination polymers on cognitive function of aged rats after anesthesia
title_full Improvement of two Mn(2+) coordination polymers on cognitive function of aged rats after anesthesia
title_fullStr Improvement of two Mn(2+) coordination polymers on cognitive function of aged rats after anesthesia
title_full_unstemmed Improvement of two Mn(2+) coordination polymers on cognitive function of aged rats after anesthesia
title_short Improvement of two Mn(2+) coordination polymers on cognitive function of aged rats after anesthesia
title_sort improvement of two mn(2+) coordination polymers on cognitive function of aged rats after anesthesia
topic Full Length Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225759/
https://www.ncbi.nlm.nih.gov/pubmed/35755881
http://dx.doi.org/10.1080/15685551.2022.2090678
work_keys_str_mv AT zhanghaolin improvementoftwomn2coordinationpolymersoncognitivefunctionofagedratsafteranesthesia
AT jiaqiang improvementoftwomn2coordinationpolymersoncognitivefunctionofagedratsafteranesthesia
AT tianfen improvementoftwomn2coordinationpolymersoncognitivefunctionofagedratsafteranesthesia
AT zhanghui improvementoftwomn2coordinationpolymersoncognitivefunctionofagedratsafteranesthesia