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An Automated Deep Learning Model for the Cerebellum Segmentation from Fetal Brain Images

Cerebellum measures taken from routinely obtained ultrasound (US) images have been frequently employed to determine gestational age and identify developing central nervous system's anatomical abnormalities. Standardized cerebellar assessments from large-scale clinical datasets are required to i...

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Autores principales: Sreelakshmy, R., Titus, Anita, Sasirekha, N., Logashanmugam, E., Begam, R. Benazir, Ramkumar, G., Raju, Raja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225853/
https://www.ncbi.nlm.nih.gov/pubmed/35757468
http://dx.doi.org/10.1155/2022/8342767
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author Sreelakshmy, R.
Titus, Anita
Sasirekha, N.
Logashanmugam, E.
Begam, R. Benazir
Ramkumar, G.
Raju, Raja
author_facet Sreelakshmy, R.
Titus, Anita
Sasirekha, N.
Logashanmugam, E.
Begam, R. Benazir
Ramkumar, G.
Raju, Raja
author_sort Sreelakshmy, R.
collection PubMed
description Cerebellum measures taken from routinely obtained ultrasound (US) images have been frequently employed to determine gestational age and identify developing central nervous system's anatomical abnormalities. Standardized cerebellar assessments from large-scale clinical datasets are required to investigate correlations between the growing cerebellum and postnatal neurodevelopmental results. These studies could uncover structural abnormalities that could be employed as indicators to forecast neurodevelopmental and growth consequences. To achieve this, higher-throughput, precise, and impartial measures must be used to replace the existing human, semiautomatic, and advanced algorithms, which seem to be time-consuming and inaccurate. In this article, we presented an innovative deep learning (DL) technique for automatic fetal cerebellum segmentation from 2-dimensional (2D) US brain images. We present ReU-Net, a semantic segmentation network tailored to the anatomy of the fetal cerebellum. Moreover, we use U-Net as a foundation models with the incorporation of residual blocks and Wiener filter over the last 2 layers to segregate the cerebellum (c) from the noisy US data. 590 images for training and 150 images for testing were taken; also, we employed a 5-fold cross-assessment method. Our ReU-Net scored 91%, 92%, 25.42, 98%, 92%, and 94% for Dice Score Coefficient (DSC), F1-score, Hausdorff Distance (HD), accuracy, recall, and precision, correspondingly. The suggested method outperforms the other U-Net predicated techniques by a quantitatively significant margin (p 0.001). Our presented approach can be used to allow high bandwidth imaging techniques in medical study fetal US images as well as biometric evaluation on a broader scale in fetal US images.
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spelling pubmed-92258532022-06-24 An Automated Deep Learning Model for the Cerebellum Segmentation from Fetal Brain Images Sreelakshmy, R. Titus, Anita Sasirekha, N. Logashanmugam, E. Begam, R. Benazir Ramkumar, G. Raju, Raja Biomed Res Int Research Article Cerebellum measures taken from routinely obtained ultrasound (US) images have been frequently employed to determine gestational age and identify developing central nervous system's anatomical abnormalities. Standardized cerebellar assessments from large-scale clinical datasets are required to investigate correlations between the growing cerebellum and postnatal neurodevelopmental results. These studies could uncover structural abnormalities that could be employed as indicators to forecast neurodevelopmental and growth consequences. To achieve this, higher-throughput, precise, and impartial measures must be used to replace the existing human, semiautomatic, and advanced algorithms, which seem to be time-consuming and inaccurate. In this article, we presented an innovative deep learning (DL) technique for automatic fetal cerebellum segmentation from 2-dimensional (2D) US brain images. We present ReU-Net, a semantic segmentation network tailored to the anatomy of the fetal cerebellum. Moreover, we use U-Net as a foundation models with the incorporation of residual blocks and Wiener filter over the last 2 layers to segregate the cerebellum (c) from the noisy US data. 590 images for training and 150 images for testing were taken; also, we employed a 5-fold cross-assessment method. Our ReU-Net scored 91%, 92%, 25.42, 98%, 92%, and 94% for Dice Score Coefficient (DSC), F1-score, Hausdorff Distance (HD), accuracy, recall, and precision, correspondingly. The suggested method outperforms the other U-Net predicated techniques by a quantitatively significant margin (p 0.001). Our presented approach can be used to allow high bandwidth imaging techniques in medical study fetal US images as well as biometric evaluation on a broader scale in fetal US images. Hindawi 2022-06-16 /pmc/articles/PMC9225853/ /pubmed/35757468 http://dx.doi.org/10.1155/2022/8342767 Text en Copyright © 2022 R. Sreelakshmy et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sreelakshmy, R.
Titus, Anita
Sasirekha, N.
Logashanmugam, E.
Begam, R. Benazir
Ramkumar, G.
Raju, Raja
An Automated Deep Learning Model for the Cerebellum Segmentation from Fetal Brain Images
title An Automated Deep Learning Model for the Cerebellum Segmentation from Fetal Brain Images
title_full An Automated Deep Learning Model for the Cerebellum Segmentation from Fetal Brain Images
title_fullStr An Automated Deep Learning Model for the Cerebellum Segmentation from Fetal Brain Images
title_full_unstemmed An Automated Deep Learning Model for the Cerebellum Segmentation from Fetal Brain Images
title_short An Automated Deep Learning Model for the Cerebellum Segmentation from Fetal Brain Images
title_sort automated deep learning model for the cerebellum segmentation from fetal brain images
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225853/
https://www.ncbi.nlm.nih.gov/pubmed/35757468
http://dx.doi.org/10.1155/2022/8342767
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