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Discovery of 2-thiobenzimidazoles as noncovalent inhibitors of SARS-CoV-2 main protease

The discovery of antiviral agents against SARS-CoV-2 is an important step toward ending the COVID-19 pandemic and to tackle future outbreaks. In this context, the main protease (M(pro)) represents an ideal target for developing coronavirus antivirals, being conserved among different strains and esse...

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Detalles Bibliográficos
Autores principales: Deodato, Davide, Asad, Nadeem, Dore, Timothy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225965/
https://www.ncbi.nlm.nih.gov/pubmed/35760254
http://dx.doi.org/10.1016/j.bmcl.2022.128867

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