Enrichment of cancer-predisposing germline variants in adult and pediatric patients with acute lymphoblastic leukemia

Despite recent progress in acute lymphoblastic leukemia (ALL) therapies, a significant subset of adult and pediatric ALL patients has a dismal prognosis. Better understanding of leukemogenesis and recognition of germline genetic changes may provide new tools for treating patients. Given that hematop...

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Detalles Bibliográficos
Autores principales: Douglas, Suvi P. M., Lahtinen, Atte K., Koski, Jessica R., Leimi, Lilli, Keränen, Mikko A. I., Koskenvuo, Minna, Heckman, Caroline A., Jahnukainen, Kirsi, Pitkänen, Esa, Wartiovaara-Kautto, Ulla, Kilpivaara, Outi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225984/
https://www.ncbi.nlm.nih.gov/pubmed/35739278
http://dx.doi.org/10.1038/s41598-022-14364-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225984/
https://www.ncbi.nlm.nih.gov/pubmed/35739278
http://dx.doi.org/10.1038/s41598-022-14364-x

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