CB1R-stabilized NLRP3 inflammasome drives antipsychotics cardiotoxicity

Long-term use of antipsychotics is a common cause of myocardial injury and even sudden cardiac deaths that often lead to drug withdrawn or discontinuation. Mechanisms underlying antipsychotics cardiotoxicity remain largely unknown. Herein we performed RNA sequencing and found that NLRP3 inflammasome...

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Detalles Bibliográficos
Autores principales: Li, Liliang, Gao, Pan, Tang, Xinru, Liu, Zheng, Cao, Mengying, Luo, Ruoyu, Li, Xiaoqing, Wang, Jing, Lin, Xinyi, Peng, Chao, Li, Zhihong, Zhang, Jianhua, Zhang, Xian, Cao, Zhonglian, Zou, Yunzeng, Jin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225989/
https://www.ncbi.nlm.nih.gov/pubmed/35739093
http://dx.doi.org/10.1038/s41392-022-01018-7

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