Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32

Emerging evidence has shown an imbalance in M1/M2 macrophage polarization to play an essential role in osteoarthritis (OA) progression. However, the underlying mechanistic basis for this polarization is unknown. RNA sequencing of OA M1-polarized macrophages found highly expressed levels of pentraxin...

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Detalles Bibliográficos
Autores principales: Yin, Jianbin, Zeng, Hua, Fan, Kai, Xie, Haoyu, Shao, Yan, Lu, Yuheng, Zhu, Jinjian, Yao, Zihao, Liu, Liangliang, Zhang, Hongbo, Luo, Bingsheng, Wang, Xinjie, Zeng, Chun, Bai, Xiaochun, Zhang, Haiyan, Cai, Daozhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226026/
https://www.ncbi.nlm.nih.gov/pubmed/35739102
http://dx.doi.org/10.1038/s41419-022-04962-y

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