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Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs

Alterations of RNA editing that affect the secondary structure of RNAs can cause human diseases. We therefore studied RNA editing in failing human hearts. Transcriptome sequencing showed that adenosine-to-inosine (A-to-I) RNA editing was responsible for 80% of the editing events in the myocardium. F...

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Detalles Bibliográficos
Autores principales:	Kokot, Karoline E., Kneuer, Jasmin M., John, David, Rebs, Sabine, Möbius-Winkler, Maximilian N., Erbe, Stephan, Müller, Marion, Andritschke, Michael, Gaul, Susanne, Sheikh, Bilal N., Haas, Jan, Thiele, Holger, Müller, Oliver J., Hille, Susanne, Leuschner, Florian, Dimmeler, Stefanie, Streckfuss-Bömeke, Katrin, Meder, Benjamin, Laufs, Ulrich, Boeckel, Jes-Niels
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Original Contribution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226085/ https://www.ncbi.nlm.nih.gov/pubmed/35737129 http://dx.doi.org/10.1007/s00395-022-00940-9

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