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Prognostic prediction of preoperative nutritional status in low-grade appendiceal mucinous neoplasms

To describe the preoperative nutritional status of Low-grade Appendiceal Mucinous Neoplasms (LAMNs) and identify prognostic factors for survival. Medical records from 165 patients with LAMNs who attended the Aerospace Center Hospital, Beijing, China between January 2017, and December 2018 were retro...

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Autores principales: Wang, Bing, Ma, Ruiqing, Shi, Guanjun, Yang, Zhenpeng, Tang, Huazhen, Lu, Shuai, Wang, Yuying, Qu, Jinxiu, Rao, Benqiang, Xu, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226184/
https://www.ncbi.nlm.nih.gov/pubmed/35739171
http://dx.doi.org/10.1038/s41598-022-14765-y
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author Wang, Bing
Ma, Ruiqing
Shi, Guanjun
Yang, Zhenpeng
Tang, Huazhen
Lu, Shuai
Wang, Yuying
Qu, Jinxiu
Rao, Benqiang
Xu, Hongbin
author_facet Wang, Bing
Ma, Ruiqing
Shi, Guanjun
Yang, Zhenpeng
Tang, Huazhen
Lu, Shuai
Wang, Yuying
Qu, Jinxiu
Rao, Benqiang
Xu, Hongbin
author_sort Wang, Bing
collection PubMed
description To describe the preoperative nutritional status of Low-grade Appendiceal Mucinous Neoplasms (LAMNs) and identify prognostic factors for survival. Medical records from 165 patients with LAMNs who attended the Aerospace Center Hospital, Beijing, China between January 2017, and December 2018 were retrospectively reviewed. Survival analysis was performed with the Kaplan–Meier method, the log-rank test, and a Cox proportional hazards model. Among 165 patients, 59 (36%) were male and 106 (64%) were female. Patient’s median age was 58 years (range 20 to 78 years). Univariate analysis indicated that gender, weight loss, prior surgical score (PSS), red blood cell, albumin, peritoneal cancer index (PCI), completeness of cytoreduction (CCR), and hyperthermic intraperitoneal chemotherapy (HIPEC) were related to prognosis. Multivariate analysis showed that PSS, CCR and HIPEC were independent predictors of prognosis. The preoperative nutritional status of patients plays an important role in predicting prognosis. Patients can benefit from a complete cytoreductive surgery (CCRS) and HIPEC in an experienced institution for the first medical treatment.
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spelling pubmed-92261842022-06-25 Prognostic prediction of preoperative nutritional status in low-grade appendiceal mucinous neoplasms Wang, Bing Ma, Ruiqing Shi, Guanjun Yang, Zhenpeng Tang, Huazhen Lu, Shuai Wang, Yuying Qu, Jinxiu Rao, Benqiang Xu, Hongbin Sci Rep Article To describe the preoperative nutritional status of Low-grade Appendiceal Mucinous Neoplasms (LAMNs) and identify prognostic factors for survival. Medical records from 165 patients with LAMNs who attended the Aerospace Center Hospital, Beijing, China between January 2017, and December 2018 were retrospectively reviewed. Survival analysis was performed with the Kaplan–Meier method, the log-rank test, and a Cox proportional hazards model. Among 165 patients, 59 (36%) were male and 106 (64%) were female. Patient’s median age was 58 years (range 20 to 78 years). Univariate analysis indicated that gender, weight loss, prior surgical score (PSS), red blood cell, albumin, peritoneal cancer index (PCI), completeness of cytoreduction (CCR), and hyperthermic intraperitoneal chemotherapy (HIPEC) were related to prognosis. Multivariate analysis showed that PSS, CCR and HIPEC were independent predictors of prognosis. The preoperative nutritional status of patients plays an important role in predicting prognosis. Patients can benefit from a complete cytoreductive surgery (CCRS) and HIPEC in an experienced institution for the first medical treatment. Nature Publishing Group UK 2022-06-23 /pmc/articles/PMC9226184/ /pubmed/35739171 http://dx.doi.org/10.1038/s41598-022-14765-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Wang, Bing
Ma, Ruiqing
Shi, Guanjun
Yang, Zhenpeng
Tang, Huazhen
Lu, Shuai
Wang, Yuying
Qu, Jinxiu
Rao, Benqiang
Xu, Hongbin
Prognostic prediction of preoperative nutritional status in low-grade appendiceal mucinous neoplasms
title Prognostic prediction of preoperative nutritional status in low-grade appendiceal mucinous neoplasms
title_full Prognostic prediction of preoperative nutritional status in low-grade appendiceal mucinous neoplasms
title_fullStr Prognostic prediction of preoperative nutritional status in low-grade appendiceal mucinous neoplasms
title_full_unstemmed Prognostic prediction of preoperative nutritional status in low-grade appendiceal mucinous neoplasms
title_short Prognostic prediction of preoperative nutritional status in low-grade appendiceal mucinous neoplasms
title_sort prognostic prediction of preoperative nutritional status in low-grade appendiceal mucinous neoplasms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226184/
https://www.ncbi.nlm.nih.gov/pubmed/35739171
http://dx.doi.org/10.1038/s41598-022-14765-y
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