LIN28 coordinately promotes nucleolar/ribosomal functions and represses the 2C-like transcriptional program in pluripotent stem cells

LIN28 is an RNA binding protein with important roles in early embryo development, stem cell differentiation/reprogramming, tumorigenesis and metabolism. Previous studies have focused mainly on its role in the cytosol where it interacts with Let-7 microRNA precursors or mRNAs, and few have addressed...

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Detalles Bibliográficos
Autores principales: Sun, Zhen, Yu, Hua, Zhao, Jing, Tan, Tianyu, Pan, Hongru, Zhu, Yuqing, Chen, Lang, Zhang, Cheng, Zhang, Li, Lei, Anhua, Xu, Yuyan, Bi, Xianju, Huang, Xin, Gao, Bo, Wang, Longfei, Correia, Cristina, Chen, Ming, Sun, Qiming, Feng, Yu, Shen, Li, Wu, Hao, Wang, Jianlong, Shen, Xiaohua, Daley, George Q., Li, Hu, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226220/
https://www.ncbi.nlm.nih.gov/pubmed/34331666
http://dx.doi.org/10.1007/s13238-021-00864-5

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