Engineering substrate specificity of HAD phosphatases and multienzyme systems development for the thermodynamic-driven manufacturing sugars

Naturally, haloacid dehalogenase superfamily phosphatases have been evolved with broad substrate promiscuity; however, strong specificity to a particular substrate is required for developing thermodynamically driven routes for manufacturing sugars. How to alter the intrinsic substrate promiscuity of...

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Detalles Bibliográficos
Autores principales: Tian, Chaoyu, Yang, Jiangang, Liu, Cui, Chen, Peng, Zhang, Tong, Men, Yan, Ma, Hongwu, Sun, Yuanxia, Ma, Yanhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226320/
https://www.ncbi.nlm.nih.gov/pubmed/35739124
http://dx.doi.org/10.1038/s41467-022-31371-8

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