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Determination of Pleiotropic Effect of Warfarin in VKORC1 and CYP2C9 Genotypes in Patients With Heart Valve Replacement

Warfarin has been widely used as an oral anticoagulant agent. In past, efforts have been done to study the contribution of genetic variation on warfarin dose requirements. The possible therapeutic dose determination of warfarin is very challenging, i.e., extremely low dose leading to unusable antith...

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Detalles Bibliográficos
Autores principales: Shafique, Huma, Ashraf, Naeem Mahmood, Rashid, Amir, Majeed, Asifa, Afsar, Tayyaba, Daly, Ann K., Almajwal, Ali, Alruwaili, Nawaf W., Khan, Azmat Ullah, Razak, Suhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226342/
https://www.ncbi.nlm.nih.gov/pubmed/35757332
http://dx.doi.org/10.3389/fcvm.2022.895169