Cargando…

Short Chain Fatty Acids Protect the Cognitive Function of Sepsis Associated Encephalopathy Mice via GPR43

OBJECTIVE: This study aims to analyze the changes of fecal short chain fatty acids (SCFAs) content and gut microbiota composition in sepsis associated encephalopathy (SAE) mice, further evaluating the effect of SCFAs on cognitive function and the underlying mechanism in SAE mice. METHODS: A total of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liao, Hongsen, Li, Haojia, Bao, Hongguang, Jiang, Li, Du, Jiayue, Guo, Yaoyi, Si, Yanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226458/ https://www.ncbi.nlm.nih.gov/pubmed/35756942 http://dx.doi.org/10.3389/fneur.2022.909436

Ejemplares similares

Disrupted metabolic and spontaneous neuronal activity of hippocampus in sepsis associated encephalopathy rats: A study combining magnetic resonance spectroscopy and resting-state functional magnetic resonance imaging
por: Li, Haojia, et al.
Publicado: (2022)

CXCR5 down-regulation alleviates cognitive dysfunction in a mouse model of sepsis-associated encephalopathy: potential role of microglial autophagy and the p38MAPK/NF-κB/STAT3 signaling pathway
por: Shen, Yanan, et al.
Publicado: (2021)

Acetate suppresses myocardial contraction via the short-chain fatty acid receptor GPR43
por: Jiang, Xuan, et al.
Publicado: (2022)

The short-chain fatty acid receptor GPR43 is transcriptionally regulated by XBP1 in human monocytes
por: Ang, Zhiwei, et al.
Publicado: (2015)

The Short-Chain Fatty Acid Receptor GPR43 Modulates YAP/TAZ via RhoA
por: Park, Bi-Oh, et al.
Publicado: (2021)

Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets
por: Ulven, Trond
Publicado: (2012)

Short Chain Fatty Acids Prevent Glyoxylate-Induced Calcium Oxalate Stones by GPR43-Dependent Immunomodulatory Mechanism
por: Jin, Xi, et al.
Publicado: (2021)

Differing roles for short chain fatty acids and GPR43 agonism in the regulation of intestinal barrier function and immune responses
por: D’Souza, Warren N., et al.
Publicado: (2017)

Application background and mechanism of short-chain fatty acids in sepsis-associated encephalopathy
por: Zhang, Qiulei, et al.
Publicado: (2023)

The Neuroprotective Effect of Short Chain Fatty Acids Against Sepsis-Associated Encephalopathy in Mice
por: Liu, Jiaming, et al.
Publicado: (2021)

The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43
por: Kimura, Ikuo, et al.
Publicado: (2013)

Knockdown of long non-coding RNA SOX2OT downregulates SOX2 to improve hippocampal neurogenesis and cognitive function in a mouse model of sepsis-associated encephalopathy
por: Yin, Jialin, et al.
Publicado: (2020)

The short chain fatty acid receptor GPR43 regulates inflammatory signals in adipose tissue M2-type macrophages
por: Nakajima, Akira, et al.
Publicado: (2017)

Insight Into Regulatory T Cells in Sepsis-Associated Encephalopathy
por: Gao, Yu-lei, et al.
Publicado: (2022)

Short-Chain Fatty Acids Ameliorate Diabetic Nephropathy via GPR43-Mediated Inhibition of Oxidative Stress and NF-κB Signaling
por: Huang, Wei, et al.
Publicado: (2020)

Microbiota metabolite short chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43
por: Wu, Wei, et al.
Publicado: (2016)

Suppression of the RAC1/MLK3/p38 Signaling Pathway by β-Elemene Alleviates Sepsis-Associated Encephalopathy in Mice
por: Pan, Cailong, et al.
Publicado: (2019)

Regulation of Sirtuin 3-Mediated Deacetylation of Cyclophilin D Attenuated Cognitive Dysfunction Induced by Sepsis-Associated Encephalopathy in Mice
por: Sun, Fan, et al.
Publicado: (2017)

Targeting the gut microbiome in the management of sepsis-associated encephalopathy
por: Barlow, Brooke, et al.
Publicado: (2022)

Bifidobacterium animalis subsp. lactis GCL2505 modulates host energy metabolism via the short-chain fatty acid receptor GPR43
por: Horiuchi, Hiroko, et al.
Publicado: (2020)

GPR43 regulation of mitochondrial damage to alleviate inflammatory reaction in sepsis
por: Zhang, Weiwei, et al.
Publicado: (2021)

Editorial: Causative mechanism and potential pharmacological and non-pharmacological interventions in sepsis-associated encephalopathy
por: Li, Yihui, et al.
Publicado: (2023)

Acetate sensing by GPR43 alarms neutrophils and protects from severe sepsis
por: Schlatterer, Katja, et al.
Publicado: (2021)

Neuroimmune Regulation in Sepsis-Associated Encephalopathy: The Interaction Between the Brain and Peripheral Immunity
por: Liu, Yu-xiao, et al.
Publicado: (2022)

Long-chain omega-3 polyunsaturated fatty acids are reduced in neonates with substantial brain injury undergoing therapeutic hypothermia after hypoxic–ischemic encephalopathy
por: Dyall, Simon C., et al.
Publicado: (2023)

The Anti-inflammatory Effects of Short Chain Fatty Acids on Lipopolysaccharide- or Tumor Necrosis Factor α-Stimulated Endothelial Cells via Activation of GPR41/43 and Inhibition of HDACs
por: Li, Meng, et al.
Publicado: (2018)

Clinical Features and Factors Associated With Sepsis-Associated Encephalopathy in Children: Retrospective Single-Center Clinical Study
por: Chen, Yihao, et al.
Publicado: (2022)

GPR41 and GPR43 in Obesity and Inflammation – Protective or Causative?
por: Ang, Zhiwei, et al.
Publicado: (2016)

Hashimoto's Encephalopathy and Seizure Disorders
por: Li, Jie, et al.
Publicado: (2019)

TDP-43 and Phosphorylated TDP-43 Levels in Paired Plasma and CSF Samples in Amyotrophic Lateral Sclerosis
por: Ren, Yuting, et al.
Publicado: (2021)

The nomogram to predict the occurrence of sepsis-associated encephalopathy in elderly patients in the intensive care units: A retrospective cohort study
por: Zhao, Qing, et al.
Publicado: (2023)

Expanding Duplication of Free Fatty Acid Receptor-2 (GPR43) Genes in the Chicken Genome
por: Meslin, Camille, et al.
Publicado: (2015)

The SCFA Receptor GPR43 and Energy Metabolism
por: Kimura, Ikuo, et al.
Publicado: (2014)

Protein modification by short-chain fatty acid metabolites in sepsis: a comprehensive review
por: Zhang, Liang, et al.
Publicado: (2023)

A Clinicopathological Report of a 93-Year-Old Former Street Boxer With Coexistence of Chronic Traumatic Encephalopathy, Alzheimer's Disease, Dementia With Lewy Bodies, and Hippocampal Sclerosis With TDP-43 Pathology
por: Yang, Chunhui, et al.
Publicado: (2020)

Heavy Cannabis Use Associated with Wernicke’s Encephalopathy
por: Chaudhari, Amit, et al.
Publicado: (2019)

Seasonal expressions of GPR41 and GPR43 in the colon of the wild ground squirrels (Spermophilus dauricus)
por: Yang, Xiaoying, et al.
Publicado: (2022)

Evaluation of the relationship between GPR43 and adiposity in human
por: Dewulf, Evelyne M, et al.
Publicado: (2013)

GPR43 Potentiates β-Cell Function in Obesity
por: McNelis, Joanne C., et al.
Publicado: (2015)

Increased whole blood FFA2/GPR43 receptor expression is associated with increased 30-day survival in patients with sepsis
por: Carr, Zyad J., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4hrvka79gnpl8ibl2f3roo8s29