Cargando…

Towards a comprehensive understanding of RNA deamination: synthesis and properties of xanthosine-modified RNA

Nucleobase deamination, such as A-to-I editing, represents an important posttranscriptional modification of RNA. When deamination affects guanosines, a xanthosine (X) containing RNA is generated. However, the biological significance and chemical consequences on RNA are poorly understood. We present...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mair, Stefan, Erharter, Kevin, Renard, Eva, Brillet, Karl, Brunner, Melanie, Lusser, Alexandra, Kreutz, Christoph, Ennifar, Eric, Micura, Ronald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226506/ https://www.ncbi.nlm.nih.gov/pubmed/35687141 http://dx.doi.org/10.1093/nar/gkac477

Ejemplares similares

Impact of 3-deazapurine nucleobases on RNA properties
por: Bereiter, Raphael, et al.
Publicado: (2021)

2′-O-Trifluoromethylated RNA – a powerful modification for RNA chemistry and NMR spectroscopy
por: Himmelstoß, Maximilian, et al.
Publicado: (2020)

AID–RNA polymerase II transcription-dependent deamination of IgV DNA
por: Pham, Phuong, et al.
Publicado: (2019)

Conformations of Flanking Bases in HIV-1 RNA DIS Kissing Complexes Studied by Molecular Dynamics
por: Réblová, Kamila, et al.
Publicado: (2007)

Zebrafish AID is capable of deaminating methylated deoxycytidines
por: Abdouni, Hala, et al.
Publicado: (2013)

The effect of adenine protonation on RNA phosphodiester backbone bond cleavage elucidated by deaza-nucleobase modifications and mass spectrometry
por: Fuchs, Elisabeth, et al.
Publicado: (2019)

Defining the functional footprint for recognition and repair of deaminated DNA
por: Baldwin, Michael R., et al.
Publicado: (2012)

Enzymatic deamination of the epigenetic nucleoside N(6)-methyladenosine regulates gene expression
por: Jiang, Zhuoran, et al.
Publicado: (2021)

Measuring deaminated nucleotide surveillance enzyme ITPA activity with an ATP-releasing nucleotide chimera
por: Ji, Debin, et al.
Publicado: (2017)

Cation-dependent cleavage of the duplex form of the subtype-B HIV-1 RNA dimerization initiation site
por: Ennifar, Eric, et al.
Publicado: (2010)

1-Deazaguanosine-Modified RNA: The Missing Piece for Functional RNA Atomic Mutagenesis
por: Bereiter, Raphael, et al.
Publicado: (2022)

Efficient deamination of 5-methylcytosines in DNA by human APOBEC3A, but not by AID or APOBEC3G
por: Wijesinghe, Priyanga, et al.
Publicado: (2012)

SHAPE probing pictures Mg(2+)-dependent folding of small self-cleaving ribozymes
por: Gasser, Catherina, et al.
Publicado: (2018)

RNA pseudoknots
por: Westhof, Eric, et al.
Publicado: (1992)

The 3′–5′ proofreading exonuclease of archaeal family-B DNA polymerase hinders the copying of template strand deaminated bases
por: Russell, Henry J., et al.
Publicado: (2009)

Structure-based investigations of the NAD(+)-II riboswitch
por: Xu, Xiaochen, et al.
Publicado: (2023)

Thioguanosine Conversion Enables mRNA‐Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC‐seq DUAL)
por: Gasser, Catherina, et al.
Publicado: (2020)

Small-molecule affinity capture of DNA/RNA quadruplexes and their identification in vitro and in vivo through the G4RP protocol
por: Renard, Isaline, et al.
Publicado: (2019)

Metabolic RNA labeling for probing RNA dynamics in bacteria
por: Meng, Liying, et al.
Publicado: (2020)

Accurate placement of substrate RNA by Gar1 in H/ACA RNA-guided pseudouridylation
por: Wang, Peng, et al.
Publicado: (2015)

Cytosolic delivery of siRNA by ultra-high affinity dsRNA binding proteins
por: Yang, Nicole J., et al.
Publicado: (2017)

Specific suppression of D-RNA G-quadruplex–protein interaction with an L-RNA aptamer
por: Umar, Mubarak I, et al.
Publicado: (2020)

Regulation of RNA editing by intracellular acidification
por: Malik, Turnee N, et al.
Publicado: (2021)

Visualization of self-delivering hydrophobically modified siRNA cellular internalization
por: Ly, Socheata, et al.
Publicado: (2017)

Repetitive RNA unwinding by RNA helicase A facilitates RNA annealing
por: Koh, Hye Ran, et al.
Publicado: (2014)

A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation
por: Desai, Kevin K., et al.
Publicado: (2014)

The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity
por: Fergus, Claire, et al.
Publicado: (2021)

Assaying RNA structure with LASER-Seq
por: Zinshteyn, Boris, et al.
Publicado: (2019)

Stability of an RNA•DNA–DNA triple helix depends on base triplet composition and length of the RNA third strand
por: Kunkler, Charlotte N, et al.
Publicado: (2019)

Partition of tRNA(Gly) isoacceptors between protein and cell-wall peptidoglycan synthesis in Staphylococcus aureus
por: Rietmeyer, Lauriane, et al.
Publicado: (2020)

Interbase FRET in RNA: from A to Z
por: Füchtbauer, Anders F, et al.
Publicado: (2019)

Cross-editing by a tRNA synthetase allows vertebrates to abundantly express mischargeable tRNA without causing mistranslation
por: Chen, Meirong, et al.
Publicado: (2020)

Subgenomic promoter recognition by the norovirus RNA-dependent RNA polymerases
por: Lin, Xiaoyan, et al.
Publicado: (2015)

RNA surveillance by uridylation-dependent RNA decay in Schizosaccharomyces pombe
por: Chung, Christina Z, et al.
Publicado: (2019)

Intermolecular ‘cross-torque’: the N(4)-cytosine propargyl residue is rotated to the ‘CH’-edge as a result of Watson–Crick interaction
por: Domingo, Olwen, et al.
Publicado: (2015)

Thermodynamic insights into 2-thiouridine-enhanced RNA hybridization
por: Larsen, Aaron T., et al.
Publicado: (2015)

Synthesis, base pairing and structure studies of geranylated RNA
por: Wang, Rui, et al.
Publicado: (2016)

Enzyme-free ligation of dimers and trimers to RNA primers
por: Sosson, Marilyne, et al.
Publicado: (2019)

Regioselective formation of RNA strands in the absence of magnesium ions
por: Motsch, Sebastian, et al.
Publicado: (2020)

tRNA(His)-guanylyltransferase establishes tRNA(His) identity
por: Heinemann, Ilka U., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_u4f4ujarjo4dv51hib5t1sa4du