Expression of Bacillus subtilis ABCF antibiotic resistance factor VmlR is regulated by RNA polymerase pausing, transcription attenuation, translation attenuation and (p)ppGpp

Since antibiotic resistance is often associated with a fitness cost, bacteria employ multi-layered regulatory mechanisms to ensure that expression of resistance factors is restricted to times of antibiotic challenge. In Bacillus subtilis, the chromosomally-encoded ABCF ATPase VmlR confers resistance...

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Detalles Bibliográficos
Autores principales: Takada, Hiraku, Mandell, Zachary F, Yakhnin, Helen, Glazyrina, Anastasiya, Chiba, Shinobu, Kurata, Tatsuaki, Wu, Kelvin J Y, Tresco, Ben I C, Myers, Andrew G, Aktinson, Gemma C, Babitzke, Paul, Hauryliuk, Vasili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226507/
https://www.ncbi.nlm.nih.gov/pubmed/35699226
http://dx.doi.org/10.1093/nar/gkac497

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