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Allosteric regulation of noncoding RNA function by microRNAs
HSUR1 and HSUR2, two noncoding RNAs expressed by the oncogenic Herpesvirus saimiri, bind host microRNAs miR-142-3p, miR-16, and miR-27 with different purposes. While binding of miR-27 to HSUR1 triggers the degradation of the microRNA, miR-16 is tethered by HSUR2 to target host mRNAs to repress their...
Autores principales: | Gorbea, Carlos, Elhakiem, Abdalla, Cazalla, Demián |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226524/ https://www.ncbi.nlm.nih.gov/pubmed/35648438 http://dx.doi.org/10.1093/nar/gkac443 |
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