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Allosteric regulation of noncoding RNA function by microRNAs

HSUR1 and HSUR2, two noncoding RNAs expressed by the oncogenic Herpesvirus saimiri, bind host microRNAs miR-142-3p, miR-16, and miR-27 with different purposes. While binding of miR-27 to HSUR1 triggers the degradation of the microRNA, miR-16 is tethered by HSUR2 to target host mRNAs to repress their...

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Detalles Bibliográficos
Autores principales: Gorbea, Carlos, Elhakiem, Abdalla, Cazalla, Demián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226524/
https://www.ncbi.nlm.nih.gov/pubmed/35648438
http://dx.doi.org/10.1093/nar/gkac443

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