Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages

Metabolic disorders (i.e., hyperglycemia, hyperlipidemia, and hyperinsulinemia) cause increased secretion of inflammatory cytokines/chemokines, leading to gradual loss of cardiac resident macrophage population and increased accumulation of inflammatory monocytes/macrophages in the heart. Such self-p...

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Detalles Bibliográficos
Autores principales: Li, Qianqian, Li, Yutian, Huang, Wei, Wang, Xiaohong, Liu, Zhenling, Chen, Jing, Fan, Yanbo, Peng, Tianqing, Sadayappan, Sakthivel, Wang, Yigang, Fan, Guo-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226549/
https://www.ncbi.nlm.nih.gov/pubmed/35757735
http://dx.doi.org/10.3389/fimmu.2022.930397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226549/
https://www.ncbi.nlm.nih.gov/pubmed/35757735
http://dx.doi.org/10.3389/fimmu.2022.930397

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