The Clinical Impact of Methotrexate-Induced Stroke-Like Neurotoxicity in Paediatric Departments: An Italian Multi-Centre Case-Series

INTRODUCTION: Stroke-like syndrome (SLS) is a rare subacute neurological complication of intrathecal or high-dose (≥500 mg) Methotrexate (MTX) administration. Its clinical features, evoking acute cerebral ischaemia with fluctuating course symptoms and a possible spontaneous resolution, have elicited...

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Detalles Bibliográficos
Autores principales: Santangelo, Andrea, Bartolini, Emanuele, Nuzzi, Giulia, Foiadelli, Thomas, Michev, Alexandre, Mina, Tommaso, Trambusti, Irene, Fichera, Valeria, Bonuccelli, Alice, Massimetti, Gabriele, Peroni, Diego G., De Marco, Emanuela, Coccoli, Luca, Luti, Laura, Bernasconi, Sayla, Nardi, Margherita, Menconi, Maria Cristina, Casazza, Gabriella, Pruna, Dario, Mura, Rosamaria, Marra, Chiara, Zama, Daniele, Striano, Pasquale, Cordelli, Duccio M., Battini, Roberta, Orsini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226576/
https://www.ncbi.nlm.nih.gov/pubmed/35756920
http://dx.doi.org/10.3389/fneur.2022.920214

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