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Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient

Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease characterized by widespread clinical manifestations and immunological disorders. A myriad of ocular manifestations can be seen in patients with SLE. The most vision-threatening complication is vaso-occlusive retinopathy including re...

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Autores principales: Ben Brahim, Marwa, Arfa, Sondes, Boubaker, Fadia, Chelly, Jihen, Ammari, Wafa, Hammami, Sonia, Arbi, Fatma, Berriche, Olfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226707/
https://www.ncbi.nlm.nih.gov/pubmed/35814626
http://dx.doi.org/10.12688/f1000research.55189.4
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author Ben Brahim, Marwa
Arfa, Sondes
Boubaker, Fadia
Chelly, Jihen
Ammari, Wafa
Hammami, Sonia
Arbi, Fatma
Berriche, Olfa
author_facet Ben Brahim, Marwa
Arfa, Sondes
Boubaker, Fadia
Chelly, Jihen
Ammari, Wafa
Hammami, Sonia
Arbi, Fatma
Berriche, Olfa
author_sort Ben Brahim, Marwa
collection PubMed
description Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease characterized by widespread clinical manifestations and immunological disorders. A myriad of ocular manifestations can be seen in patients with SLE. The most vision-threatening complication is vaso-occlusive retinopathy including retinal vein occlusion (RVO). RVO associated with SLE is well described in the literature and its association with antiphospholipid antibodies is recognized. However, RVO as the initial manifestation of SLE is scarcely reported. Herein, we report the first case of recurrent RVO as the revealing manifestation of SLE in a 40-year-old male patient. He had two consecutive episodes of decreased vision. Ophthalmologic examination disclosed a branch retinal vein occlusion the first time and a central retinal vein occlusion the second time. The diagnosis of SLE was established based on clinical and immunological criteria. He was prescribed antiplatelet therapy, hydroxychloroquine at 5.5 mg/kg/day, and intravitreal anti-vascular endothelial growth factor (VEGF) antibodies regimen. He slowly improved under treatment.
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spelling pubmed-92267072022-07-08 Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient Ben Brahim, Marwa Arfa, Sondes Boubaker, Fadia Chelly, Jihen Ammari, Wafa Hammami, Sonia Arbi, Fatma Berriche, Olfa F1000Res Case Report Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease characterized by widespread clinical manifestations and immunological disorders. A myriad of ocular manifestations can be seen in patients with SLE. The most vision-threatening complication is vaso-occlusive retinopathy including retinal vein occlusion (RVO). RVO associated with SLE is well described in the literature and its association with antiphospholipid antibodies is recognized. However, RVO as the initial manifestation of SLE is scarcely reported. Herein, we report the first case of recurrent RVO as the revealing manifestation of SLE in a 40-year-old male patient. He had two consecutive episodes of decreased vision. Ophthalmologic examination disclosed a branch retinal vein occlusion the first time and a central retinal vein occlusion the second time. The diagnosis of SLE was established based on clinical and immunological criteria. He was prescribed antiplatelet therapy, hydroxychloroquine at 5.5 mg/kg/day, and intravitreal anti-vascular endothelial growth factor (VEGF) antibodies regimen. He slowly improved under treatment. F1000 Research Limited 2022-06-22 /pmc/articles/PMC9226707/ /pubmed/35814626 http://dx.doi.org/10.12688/f1000research.55189.4 Text en Copyright: © 2022 Ben Brahim M et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ben Brahim, Marwa
Arfa, Sondes
Boubaker, Fadia
Chelly, Jihen
Ammari, Wafa
Hammami, Sonia
Arbi, Fatma
Berriche, Olfa
Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient
title Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient
title_full Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient
title_fullStr Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient
title_full_unstemmed Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient
title_short Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient
title_sort case report: recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226707/
https://www.ncbi.nlm.nih.gov/pubmed/35814626
http://dx.doi.org/10.12688/f1000research.55189.4
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