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IL-17 Induces Autophagy Dysfunction to Promote Inflammatory Cell Death and Fibrosis in Keloid Fibroblasts via the STAT3 and HIF-1α Dependent Signaling Pathways

Keloid is an abnormal fibrotic disease after cutaneous injury characterized by exaggerated scar tissue formation, which often extends beyond the boundaries of the original wound. Although chronic inflammation is known to be associated with the excessive inflammation in keloid tissue, there are few s...

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Detalles Bibliográficos
Autores principales: Lee, Seon-Yeong, Lee, A Ram, Choi, Jeong Won, Lee, Chae Rim, Cho, Keun-Hyung, Lee, Jung Ho, Cho, Mi-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226909/
https://www.ncbi.nlm.nih.gov/pubmed/35757697
http://dx.doi.org/10.3389/fimmu.2022.888719