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IL-17 Induces Autophagy Dysfunction to Promote Inflammatory Cell Death and Fibrosis in Keloid Fibroblasts via the STAT3 and HIF-1α Dependent Signaling Pathways
Keloid is an abnormal fibrotic disease after cutaneous injury characterized by exaggerated scar tissue formation, which often extends beyond the boundaries of the original wound. Although chronic inflammation is known to be associated with the excessive inflammation in keloid tissue, there are few s...
Autores principales: | Lee, Seon-Yeong, Lee, A Ram, Choi, Jeong Won, Lee, Chae Rim, Cho, Keun-Hyung, Lee, Jung Ho, Cho, Mi-La |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226909/ https://www.ncbi.nlm.nih.gov/pubmed/35757697 http://dx.doi.org/10.3389/fimmu.2022.888719 |
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