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Nanoparticle delivery of miR-21-3p sensitizes melanoma to anti-PD-1 immunotherapy by promoting ferroptosis

BACKGROUND: Although anti-programmed cell death protein 1 (PD-1) immunotherapy is greatly effective in melanoma treatment, low response rate and treatment resistance significantly hinder its efficacy. Tumor cell ferroptosis triggered by interferon (IFN)-γ that is derived from tumor-infiltrating CD8(...

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Detalles Bibliográficos
Autores principales:	Guo, Weinan, Wu, Zhenjie, Chen, Jianru, Guo, Sen, You, Weiming, Wang, Sijia, Ma, Jinyuan, Wang, Huina, Wang, Xiangxu, Wang, Hao, Ma, Jingjing, Yang, Yuqi, Tian, Yangzi, Shi, Qiong, Gao, Tianwen, Yi, Xiuli, Li, Chunying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Clinical/Translational Cancer Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226924/ https://www.ncbi.nlm.nih.gov/pubmed/35738798 http://dx.doi.org/10.1136/jitc-2021-004381

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