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Ingenious Action of Vibrio cholerae Neuraminidase Recruiting Additional GM1 Cholera Toxin Receptors for Primary Human Colon Epithelial Cells

For five decades it has been known that the pentamer of B subunits (choleragenoid) of the cholera toxin (CT) of Vibrio cholerae binds with high preference to the ganglioside GM1 (II(3)Neu5Ac-Gg4Cer). However, the exact structures of CT-binding GM1 lipoforms of primary human colon epithelial cells (p...

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Detalles Bibliográficos
Autores principales: Detzner, Johanna, Püttmann, Charlotte, Pohlentz, Gottfried, Müthing, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227022/
https://www.ncbi.nlm.nih.gov/pubmed/35744773
http://dx.doi.org/10.3390/microorganisms10061255