Cargando…

CRISPR/Cas9-Mediated Disruption of the lef8 and lef9 to Inhibit Nucleopolyhedrovirus Replication in Silkworms

Bombyx mori nucleopolyhedrovirus (BmNPV) is a pathogen that causes severe disease in silkworms. In a previous study, we demonstrated that by using the CRISPR/Cas9 system to disrupt the BmNPV ie-1 and me53 genes, transgenic silkworms showed resistance to BmNPV infection. Here, we used the same strate...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yujia, Zhang, Xiaoqian, Chen, Dongbin, Yang, Dehong, Zhu, Chenxu, Tang, Linmeng, Yang, Xu, Wang, Yaohui, Luo, Xingyu, Wang, Manli, Huang, Yongping, Hu, Zhihong, Liu, Zulian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227026/
https://www.ncbi.nlm.nih.gov/pubmed/35746591
http://dx.doi.org/10.3390/v14061119