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CRISPR/Cas9-Mediated Disruption of the lef8 and lef9 to Inhibit Nucleopolyhedrovirus Replication in Silkworms
Bombyx mori nucleopolyhedrovirus (BmNPV) is a pathogen that causes severe disease in silkworms. In a previous study, we demonstrated that by using the CRISPR/Cas9 system to disrupt the BmNPV ie-1 and me53 genes, transgenic silkworms showed resistance to BmNPV infection. Here, we used the same strate...
Autores principales: | Liu, Yujia, Zhang, Xiaoqian, Chen, Dongbin, Yang, Dehong, Zhu, Chenxu, Tang, Linmeng, Yang, Xu, Wang, Yaohui, Luo, Xingyu, Wang, Manli, Huang, Yongping, Hu, Zhihong, Liu, Zulian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227026/ https://www.ncbi.nlm.nih.gov/pubmed/35746591 http://dx.doi.org/10.3390/v14061119 |
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