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Recombinant BCG-LTAK63 Vaccine Candidate for Tuberculosis Induces an Inflammatory Profile in Human Macrophages
Tuberculosis (TB) is one of the top 10 leading causes of death worldwide. The recombinant BCG strain expressing the genetically detoxified A subunit of the thermolabile toxin from Escherichia coli (LTAK63) adjuvant (rBCG-LTAK63) has previously been shown to confer superior protection and immunogenic...
Autores principales: | dos Santos, Carina C., Walburg, Kimberley V., van Veen, Suzanne, Wilson, Louis G., Trufen, Carlos E. M., Nascimento, Ivan P., Ottenhoff, Tom H. M., Leite, Luciana C. C., Haks, Mariëlle C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227035/ https://www.ncbi.nlm.nih.gov/pubmed/35746439 http://dx.doi.org/10.3390/vaccines10060831 |
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