Cargando…

Tetanus Toxin Fragment C: Structure, Drug Discovery Research and Production

Tetanus toxoid (TTd) plays an important role in the pharmaceutical world, especially in vaccines. The toxoid is obtained after formaldehyde treatment of the tetanus toxin. In parallel, current emphasis in the drug discovery field is put on producing well-defined and safer drugs, explaining the inter...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bayart, Caroline, Mularoni, Angélique, Hemmani, Nada, Kerachni, Soumeya, Jose, Joachim, Gouet, Patrice, Paladino, Joseph, Le Borgne, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227095/ https://www.ncbi.nlm.nih.gov/pubmed/35745675 http://dx.doi.org/10.3390/ph15060756

Ejemplares similares

Tetanus Toxin C-Fragment: The Courier and the Cure?
por: Toivonen, Janne M., et al.
Publicado: (2010)

Fragment C of Tetanus Toxin: New Insights into Its Neuronal Signaling Pathway
por: Calvo, Ana C., et al.
Publicado: (2012)

Tetanus Toxin and Antitoxin
por: McFarland, Joseph, et al.
Publicado: (1899)

Tetanus Toxin and Antitoxin
por: McFarland, Joseph, et al.
Publicado: (1899)

Tetanus toxin fragment C fused to flagellin makes a potent mucosal vaccine
por: Lee, Shee Eun, et al.
Publicado: (2015)

Production and Characterization of Recombinant Light Chain and Carboxyterminal Heavy Chain Fragments of Tetanus Toxin
por: Yousefi, Mehdi, et al.
Publicado: (2013)

Tetanus toxin fragments and Bcl-2 fusion proteins: cytoprotection and retrograde axonal migration
por: Watanabe, Yasuhiro, et al.
Publicado: (2018)

Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo
por: Netzahualcoyotzi, Citlalli, et al.
Publicado: (2018)

Neuroprotective Fragment C of Tetanus Toxin Modulates IL-6 in an ALS Mouse Model
por: Moreno-Martinez, Laura, et al.
Publicado: (2020)

Confocal Endomicroscopy of Neuromuscular Junctions Stained with Physiologically Inert Protein Fragments of Tetanus Toxin
por: Roesl, Cornelia, et al.
Publicado: (2021)

The Immunogenicity of the C Fragment of Tetanus Neurotoxin in Production of Tetanus Antitoxin
por: Yu, Rui, et al.
Publicado: (2018)

The Effect of Cysteine on Tetanus Toxin
por: Cowles, Philip B.
Publicado: (1936)

Fragment C Domain of Tetanus Toxin Mitigates Methamphetamine Neurotoxicity and Its Motor Consequences in Mice
por: Mendieta, Liliana, et al.
Publicado: (2016)

The Pneumococcal Polysaccharide-Tetanus Toxin Native C-Fragment Conjugate Vaccine: The Carrier Effect and Immunogenicity
por: Yu, Rui, et al.
Publicado: (2020)

1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery
por: Raingeval, Claire, et al.
Publicado: (2019)

THE EFFECT OF EOSIN UPON TETANUS TOXIN AND UPON TETANUS IN RATS AND GUINEA-PIGS
por: Flexner, Simon, et al.
Publicado: (1906)

Tetanus Toxin Hc Fragment Induces the Formation of Ceramide Platforms and Protects Neuronal Cells against Oxidative Stress
por: Cubí, Roger, et al.
Publicado: (2013)

Therapeutic Assay with the Non-toxic C-Terminal Fragment of Tetanus Toxin (TTC) in Transgenic Murine Models of Prion Disease
por: Betancor, Marina, et al.
Publicado: (2021)

Tetanus: Pathophysiology, Treatment, and the Possibility of Using Botulinum Toxin against Tetanus-Induced Rigidity and Spasms
por: Hassel, Bjørnar
Publicado: (2013)

Recent Researches on Tetanus
por: Hewlett, R. T.
Publicado: (1894)

THE LOCALIZED ACTION ON THE SPINAL CORD OF INTRAMUSCULARLY INJECTED TETANUS TOXIN
por: Acheson, George H., et al.
Publicado: (1942)

THE RELATIONSHIP OF TOXIN AND ANTITOXIN INJECTION SITE TO TETANUS DEVELOPMENT IN THE RAT
por: Fedinec, Alexander A., et al.
Publicado: (1959)

Tetanus Toxin cis-Loop Contributes to Light-Chain Translocation
por: Zuverink, Madison, et al.
Publicado: (2020)

THE INFLUENCE OF CONCENTRATION (GIBSON'S METHOD) ON THE PRESENCE OF TETANUS TOXIN IN BLOOD SERUM
por: Anderson, John F.
Publicado: (1909)

The Peptide Network between Tetanus Toxin and Human Proteins Associated with Epilepsy
por: Lucchese, Guglielmo, et al.
Publicado: (2014)

Genetically detoxified tetanus toxin as a vaccine and conjugate carrier protein
por: Chang, Min-Ju, et al.
Publicado: (2022)

Neuroprotective Effect of Non-viral Gene Therapy Treatment Based on Tetanus Toxin C-fragment in a Severe Mouse Model of Spinal Muscular Atrophy
por: Oliván, Sara, et al.
Publicado: (2016)

The Effect of Lysozyme on the Production of Tetanus Toxin. II. Mouse M.L.D.
por: Stone, Joseph L.
Publicado: (1953)

Structural and functional substrates of tetanus toxin in an animal model of temporal lobe epilepsy
por: Ferecskó, Alex S., et al.
Publicado: (2014)

An oligoclonal combination of human monoclonal antibodies able to neutralize tetanus toxin in vivo
por: Aliprandini, Eduardo, et al.
Publicado: (2019)

Functional display of heterotetrameric human protein kinase CK2 on Escherichia coli: a novel tool for drug discovery
por: Gratz, Andreas, et al.
Publicado: (2015)

Inhibition of Shiga toxin-converting bacteriophage development by novel antioxidant compounds
por: Bloch, Sylwia, et al.
Publicado: (2018)

Fate of tetanus toxin bound to the surface of primary neurons in culture: evidence for rapid internalization
Publicado: (1985)

Synthetic Cannabinoid-Induced Immunosuppression Augments Cerebellar Dysfunction in Tetanus-Toxin Treated Mice
por: Yun, Jaesuk, et al.
Publicado: (2017)

Characterization and evaluation of the enzymatic activity of tetanus toxin submitted to cobalt-60 gamma radiation
por: Sartori, Giselle Pacifico, et al.
Publicado: (2021)

Tetanus
Publicado: (1900)

Tetanus
por: Gupta, Hari Charan
Publicado: (1916)

Tetanus
Publicado: (1889)

On Tetanus
por: Macnamara, C.
Publicado: (1872)

On Tetanus
por: Macnamara, C.
Publicado: (1872)

Cannot write session to /tmp/vufind_sessions/sess_4mrgn5biad5719p1dfo1kckqcu