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Activation of the zinc-sensing receptor GPR39 promotes T-cell reconstitution after hematopoietic cell transplant in mice

Prolonged lymphopenia represents a major clinical problem after cytoreductive therapies such as chemotherapy and the conditioning required for hematopoietic stem cell transplant (HCT), contributing to the risk of infections and malignant relapse. Restoration of T-cell immunity depends on tissue rege...

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Detalles Bibliográficos
Autores principales:	Iovino, Lorenzo, Cooper, Kirsten, deRoos, Paul, Kinsella, Sinéad, Evandy, Cindy, Ugrai, Tamas, Mazziotta, Francesco, Ensbey, Kathleen S., Granadier, David, Hopwo, Kayla, Smith, Colton, Gagnon, Alex, Galimberti, Sara, Petrini, Mario, Hill, Geoffrey R., Dudakov, Jarrod A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2022
Materias:	Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227099/ https://www.ncbi.nlm.nih.gov/pubmed/35357432 http://dx.doi.org/10.1182/blood.2021013950

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