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Characterization of Aurintricarboxylic Acid (ATA) Interactions with Plasma Transporter Protein and SARS-CoV-2 Viral Targets: Correlation of Functional Activity and Binding Energetics

In an effort to identify functional-energetic correlations leading to the development of efficient anti-SARS-CoV-2 therapeutic agents, we have designed synthetic analogs of aurintricarboxylic acid (ATA), a heterogeneous polymeric mixture of structurally related linear homologs known to exhibit a hos...

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Detalles Bibliográficos
Autores principales: Minetti, Conceição A., Remeta, David P., Hashimoto, Keiji, Bonala, Radha, Chennamshetti, Rajesh, Yin, Xingyu, Garcia-Diaz, Miguel, Grollman, Arthur P., Johnson, Francis, Sidorenko, Viktoriya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227171/
https://www.ncbi.nlm.nih.gov/pubmed/35743905
http://dx.doi.org/10.3390/life12060872