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B Vitamins and Their Roles in Gut Health

B vitamins act as coenzymes in a myriad of cellular reactions. These include energy production, methyl donor generation, neurotransmitter synthesis, and immune functions. Due to the ubiquitous roles of these vitamins, their deficiencies significantly affect the host’s metabolism. Recently, novel rol...

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Autores principales: Hossain, Khandkar Shaharina, Amarasena, Sathya, Mayengbam, Shyamchand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227236/
https://www.ncbi.nlm.nih.gov/pubmed/35744686
http://dx.doi.org/10.3390/microorganisms10061168
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author Hossain, Khandkar Shaharina
Amarasena, Sathya
Mayengbam, Shyamchand
author_facet Hossain, Khandkar Shaharina
Amarasena, Sathya
Mayengbam, Shyamchand
author_sort Hossain, Khandkar Shaharina
collection PubMed
description B vitamins act as coenzymes in a myriad of cellular reactions. These include energy production, methyl donor generation, neurotransmitter synthesis, and immune functions. Due to the ubiquitous roles of these vitamins, their deficiencies significantly affect the host’s metabolism. Recently, novel roles of B vitamins in the homeostasis of gut microbial ecology and intestinal health continue to be unravelled. This review focuses on the functional roles and biosynthesis of B vitamins and how these vitamins influence the growth and proliferation of the gut microbiota. We have identified the gut bacteria that can produce vitamins, and their biosynthetic mechanisms are presented. The effects of B vitamin deficiencies on intestinal morphology, inflammation, and its effects on intestinal disorders are also discussed.
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spelling pubmed-92272362022-06-25 B Vitamins and Their Roles in Gut Health Hossain, Khandkar Shaharina Amarasena, Sathya Mayengbam, Shyamchand Microorganisms Review B vitamins act as coenzymes in a myriad of cellular reactions. These include energy production, methyl donor generation, neurotransmitter synthesis, and immune functions. Due to the ubiquitous roles of these vitamins, their deficiencies significantly affect the host’s metabolism. Recently, novel roles of B vitamins in the homeostasis of gut microbial ecology and intestinal health continue to be unravelled. This review focuses on the functional roles and biosynthesis of B vitamins and how these vitamins influence the growth and proliferation of the gut microbiota. We have identified the gut bacteria that can produce vitamins, and their biosynthetic mechanisms are presented. The effects of B vitamin deficiencies on intestinal morphology, inflammation, and its effects on intestinal disorders are also discussed. MDPI 2022-06-07 /pmc/articles/PMC9227236/ /pubmed/35744686 http://dx.doi.org/10.3390/microorganisms10061168 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hossain, Khandkar Shaharina
Amarasena, Sathya
Mayengbam, Shyamchand
B Vitamins and Their Roles in Gut Health
title B Vitamins and Their Roles in Gut Health
title_full B Vitamins and Their Roles in Gut Health
title_fullStr B Vitamins and Their Roles in Gut Health
title_full_unstemmed B Vitamins and Their Roles in Gut Health
title_short B Vitamins and Their Roles in Gut Health
title_sort b vitamins and their roles in gut health
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227236/
https://www.ncbi.nlm.nih.gov/pubmed/35744686
http://dx.doi.org/10.3390/microorganisms10061168
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