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B Vitamins and Their Roles in Gut Health
B vitamins act as coenzymes in a myriad of cellular reactions. These include energy production, methyl donor generation, neurotransmitter synthesis, and immune functions. Due to the ubiquitous roles of these vitamins, their deficiencies significantly affect the host’s metabolism. Recently, novel rol...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227236/ https://www.ncbi.nlm.nih.gov/pubmed/35744686 http://dx.doi.org/10.3390/microorganisms10061168 |
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author | Hossain, Khandkar Shaharina Amarasena, Sathya Mayengbam, Shyamchand |
author_facet | Hossain, Khandkar Shaharina Amarasena, Sathya Mayengbam, Shyamchand |
author_sort | Hossain, Khandkar Shaharina |
collection | PubMed |
description | B vitamins act as coenzymes in a myriad of cellular reactions. These include energy production, methyl donor generation, neurotransmitter synthesis, and immune functions. Due to the ubiquitous roles of these vitamins, their deficiencies significantly affect the host’s metabolism. Recently, novel roles of B vitamins in the homeostasis of gut microbial ecology and intestinal health continue to be unravelled. This review focuses on the functional roles and biosynthesis of B vitamins and how these vitamins influence the growth and proliferation of the gut microbiota. We have identified the gut bacteria that can produce vitamins, and their biosynthetic mechanisms are presented. The effects of B vitamin deficiencies on intestinal morphology, inflammation, and its effects on intestinal disorders are also discussed. |
format | Online Article Text |
id | pubmed-9227236 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92272362022-06-25 B Vitamins and Their Roles in Gut Health Hossain, Khandkar Shaharina Amarasena, Sathya Mayengbam, Shyamchand Microorganisms Review B vitamins act as coenzymes in a myriad of cellular reactions. These include energy production, methyl donor generation, neurotransmitter synthesis, and immune functions. Due to the ubiquitous roles of these vitamins, their deficiencies significantly affect the host’s metabolism. Recently, novel roles of B vitamins in the homeostasis of gut microbial ecology and intestinal health continue to be unravelled. This review focuses on the functional roles and biosynthesis of B vitamins and how these vitamins influence the growth and proliferation of the gut microbiota. We have identified the gut bacteria that can produce vitamins, and their biosynthetic mechanisms are presented. The effects of B vitamin deficiencies on intestinal morphology, inflammation, and its effects on intestinal disorders are also discussed. MDPI 2022-06-07 /pmc/articles/PMC9227236/ /pubmed/35744686 http://dx.doi.org/10.3390/microorganisms10061168 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Hossain, Khandkar Shaharina Amarasena, Sathya Mayengbam, Shyamchand B Vitamins and Their Roles in Gut Health |
title | B Vitamins and Their Roles in Gut Health |
title_full | B Vitamins and Their Roles in Gut Health |
title_fullStr | B Vitamins and Their Roles in Gut Health |
title_full_unstemmed | B Vitamins and Their Roles in Gut Health |
title_short | B Vitamins and Their Roles in Gut Health |
title_sort | b vitamins and their roles in gut health |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227236/ https://www.ncbi.nlm.nih.gov/pubmed/35744686 http://dx.doi.org/10.3390/microorganisms10061168 |
work_keys_str_mv | AT hossainkhandkarshaharina bvitaminsandtheirrolesinguthealth AT amarasenasathya bvitaminsandtheirrolesinguthealth AT mayengbamshyamchand bvitaminsandtheirrolesinguthealth |