Activation of LXRs Reduces Oxysterol Lipotoxicity in RPE Cells by Promoting Mitochondrial Function

Effective treatments for age-related macular degeneration (AMD), the most prevalent neurodegenerative form of blindness in older adults, are lacking. Genome-wide association studies have identified lipid metabolism and inflammation as AMD-associated pathogenic changes. Liver X receptors (LXRs) play...

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Detalles Bibliográficos
Autores principales: Xie, Lirong, Gu, Qing, Wu, Xingwei, Yin, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227277/
https://www.ncbi.nlm.nih.gov/pubmed/35745203
http://dx.doi.org/10.3390/nu14122473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227277/
https://www.ncbi.nlm.nih.gov/pubmed/35745203
http://dx.doi.org/10.3390/nu14122473

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