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Subcutaneous and Intraosseous Fat Necrosis Associated with Chronic Pancreatitis

Background: Extra-abdominal manifestations of fat necrosis, like subcutaneous fat necrosis, polyarthritis, and polyserositis may appear with an occurrence rate of about 0.8%, wherein intraosseous fat necrosis is a more rare complication of pancreatitis, with few reports in English literature. Case r...

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Autores principales: Zivadinovic, Jelena D., Stojanovic, Marko M., Stosic, Marija D., Zivadinovic, Aleksandar R., Jankovic, Radmilo, Gmijovic, Marko D., Golubovic, Ilija, Stosic, Biljana, Ignjatovic, Nebojsa S., Stojanovic, Miroslav P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227301/
https://www.ncbi.nlm.nih.gov/pubmed/35744065
http://dx.doi.org/10.3390/medicina58060802
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author Zivadinovic, Jelena D.
Stojanovic, Marko M.
Stosic, Marija D.
Zivadinovic, Aleksandar R.
Jankovic, Radmilo
Gmijovic, Marko D.
Golubovic, Ilija
Stosic, Biljana
Ignjatovic, Nebojsa S.
Stojanovic, Miroslav P.
author_facet Zivadinovic, Jelena D.
Stojanovic, Marko M.
Stosic, Marija D.
Zivadinovic, Aleksandar R.
Jankovic, Radmilo
Gmijovic, Marko D.
Golubovic, Ilija
Stosic, Biljana
Ignjatovic, Nebojsa S.
Stojanovic, Miroslav P.
author_sort Zivadinovic, Jelena D.
collection PubMed
description Background: Extra-abdominal manifestations of fat necrosis, like subcutaneous fat necrosis, polyarthritis, and polyserositis may appear with an occurrence rate of about 0.8%, wherein intraosseous fat necrosis is a more rare complication of pancreatitis, with few reports in English literature. Case report: A 34-year-old male with a 15-year-history of alcohol abuse was hospitalized several times in the last few years because of attacks of relapsed chronic pancreatitis. After the last attack, pancreatitis came in a stable state (“burned out”) with no symptoms and signs of the disease. The patient had been free of symptoms for 28 months since the last admission when he came with sub-febrile temperature, huge pain, swelling, and erythema in the area of the left lateral malleolar region with propagation in the foot. Blood biochemistry was normal. Conventional radiography showed multiple sites of osteolysis in the left calcaneus. Images on multislice computed tomography (MSCT) with 3D reconstruction revealed hypodense focuses that corresponded to osteonecrosis areas and bone marrow edema in the left calcaneus. Conclusions: The possibility of intraosseous fat necrosis should be considered in situations of unexplained polyarthritis or panniculitis, particularly in individuals with alcohol abuse or pancreatic disease.
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spelling pubmed-92273012022-06-25 Subcutaneous and Intraosseous Fat Necrosis Associated with Chronic Pancreatitis Zivadinovic, Jelena D. Stojanovic, Marko M. Stosic, Marija D. Zivadinovic, Aleksandar R. Jankovic, Radmilo Gmijovic, Marko D. Golubovic, Ilija Stosic, Biljana Ignjatovic, Nebojsa S. Stojanovic, Miroslav P. Medicina (Kaunas) Case Report Background: Extra-abdominal manifestations of fat necrosis, like subcutaneous fat necrosis, polyarthritis, and polyserositis may appear with an occurrence rate of about 0.8%, wherein intraosseous fat necrosis is a more rare complication of pancreatitis, with few reports in English literature. Case report: A 34-year-old male with a 15-year-history of alcohol abuse was hospitalized several times in the last few years because of attacks of relapsed chronic pancreatitis. After the last attack, pancreatitis came in a stable state (“burned out”) with no symptoms and signs of the disease. The patient had been free of symptoms for 28 months since the last admission when he came with sub-febrile temperature, huge pain, swelling, and erythema in the area of the left lateral malleolar region with propagation in the foot. Blood biochemistry was normal. Conventional radiography showed multiple sites of osteolysis in the left calcaneus. Images on multislice computed tomography (MSCT) with 3D reconstruction revealed hypodense focuses that corresponded to osteonecrosis areas and bone marrow edema in the left calcaneus. Conclusions: The possibility of intraosseous fat necrosis should be considered in situations of unexplained polyarthritis or panniculitis, particularly in individuals with alcohol abuse or pancreatic disease. MDPI 2022-06-14 /pmc/articles/PMC9227301/ /pubmed/35744065 http://dx.doi.org/10.3390/medicina58060802 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Zivadinovic, Jelena D.
Stojanovic, Marko M.
Stosic, Marija D.
Zivadinovic, Aleksandar R.
Jankovic, Radmilo
Gmijovic, Marko D.
Golubovic, Ilija
Stosic, Biljana
Ignjatovic, Nebojsa S.
Stojanovic, Miroslav P.
Subcutaneous and Intraosseous Fat Necrosis Associated with Chronic Pancreatitis
title Subcutaneous and Intraosseous Fat Necrosis Associated with Chronic Pancreatitis
title_full Subcutaneous and Intraosseous Fat Necrosis Associated with Chronic Pancreatitis
title_fullStr Subcutaneous and Intraosseous Fat Necrosis Associated with Chronic Pancreatitis
title_full_unstemmed Subcutaneous and Intraosseous Fat Necrosis Associated with Chronic Pancreatitis
title_short Subcutaneous and Intraosseous Fat Necrosis Associated with Chronic Pancreatitis
title_sort subcutaneous and intraosseous fat necrosis associated with chronic pancreatitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227301/
https://www.ncbi.nlm.nih.gov/pubmed/35744065
http://dx.doi.org/10.3390/medicina58060802
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