Heparin Protects Severe Acute Pancreatitis by Inhibiting HMGB-1 Active Secretion from Macrophages

Heparin has shown benefits in severe acute pancreatitis (SAP) therapy, but the underlying mechanisms were unknown. Extracellular high-mobility group protein-1 (HMGB-1) has been regarded as a central mediator contributing to inflammation exacerbation and disease aggravation. We hypothesized heparin a...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Jing, Tang, Xujiao, Wu, Qingqing, Ren, Panpan, Yan, Yishu, Liu, Wei, Pan, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227308/
https://www.ncbi.nlm.nih.gov/pubmed/35746047
http://dx.doi.org/10.3390/polym14122470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227308/
https://www.ncbi.nlm.nih.gov/pubmed/35746047
http://dx.doi.org/10.3390/polym14122470

Ejemplares similares