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Heparin Protects Severe Acute Pancreatitis by Inhibiting HMGB-1 Active Secretion from Macrophages

Heparin has shown benefits in severe acute pancreatitis (SAP) therapy, but the underlying mechanisms were unknown. Extracellular high-mobility group protein-1 (HMGB-1) has been regarded as a central mediator contributing to inflammation exacerbation and disease aggravation. We hypothesized heparin a...

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Detalles Bibliográficos
Autores principales:	Yang, Jing, Tang, Xujiao, Wu, Qingqing, Ren, Panpan, Yan, Yishu, Liu, Wei, Pan, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227308/ https://www.ncbi.nlm.nih.gov/pubmed/35746047 http://dx.doi.org/10.3390/polym14122470

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