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Computational Investigations of Traditional Chinese Medicinal Compounds against the Omicron Variant of SARS-CoV-2 to Rescue the Host Immune System
Macrodomain-I of the NSP3 (non-structural protein 3) is responsible for immune response hijacking in the SARS-CoV-2 infection known as COVID-19. In the omicron variant (B.1.1.529), this domain harbors a new mutation, V1069I, which may increase the binding of ADPr and consequently the infection sever...
Autores principales: | Naman, Ziad Tareq, Kadhim, Salim, Al-Isawi, Zahraa J. K., Butch, Christopher J., Muhseen, Ziyad Tariq |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227372/ https://www.ncbi.nlm.nih.gov/pubmed/35745660 http://dx.doi.org/10.3390/ph15060741 |
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