Cargando…

Discovery of Novel Coumarin Derivatives as Potential Dual Inhibitors against α-Glucosidase and α-Amylase for the Management of Post-Prandial Hyperglycemia via Molecular Modelling Approaches

Coumarin derivatives are proven for their therapeutic uses in several human diseases and disorders such as inflammation, neurodegenerative disorders, cancer, fertility, and microbial infections. Coumarin derivatives and coumarin-based scaffolds gained renewed attention for treating diabetes mellitus...

Descripción completa

Detalles Bibliográficos
Autores principales:	Patil, Shashank M., Martiz, Reshma Mary, Satish, A. M., Shbeer, Abdullah M., Ageel, Mohammed, Al-Ghorbani, Mohammed, Ranganatha, Lakshmi, Parameswaran, Saravanan, Ramu, Ramith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227442/ https://www.ncbi.nlm.nih.gov/pubmed/35745030 http://dx.doi.org/10.3390/molecules27123888

Ejemplares similares

Probiotic Potential Lacticaseibacillus casei and Limosilactobacillus fermentum Strains Isolated from Dosa Batter Inhibit α-Glucosidase and α-Amylase Enzymes
por: Kumari V. B., Chandana, et al.
Publicado: (2022)

Phyto-Computational Intervention of Diabetes Mellitus at Multiple Stages Using Isoeugenol from Ocimum tenuiflorum: A Combination of Pharmacokinetics and Molecular Modelling Approaches
por: Martiz, Reshma Mary, et al.
Publicado: (2022)

Computer-Aided Screening of Phytoconstituents from Ocimum tenuiflorum against Diabetes Mellitus Targeting DPP4 Inhibition: A Combination of Molecular Docking, Molecular Dynamics, and Pharmacokinetics Approaches
por: Sajal, Harshit, et al.
Publicado: (2022)

Inhibitory Effect of Polyphenols from the Whole Green Jackfruit Flour against α-Glucosidase, α-Amylase, Aldose Reductase and Glycation at Multiple Stages and Their Interaction: Inhibition Kinetics and Molecular Simulations
por: Maradesha, Tejaswini, et al.
Publicado: (2022)

Inhibitors of α‐amylase and α‐glucosidase: Potential linkage for whole cereal foods on prevention of hyperglycemia
por: Gong, Lingxiao, et al.
Publicado: (2020)

Isolation and characterization of lactic acid bacteria with potential probiotic activity and further investigation of their activity by α-amylase and α-glucosidase inhibitions of fermented batters
por: Huligere, Sujay S., et al.
Publicado: (2023)

Benzodioxole grafted spirooxindole pyrrolidinyl derivatives: synthesis, characterization, molecular docking and anti-diabetic activity
por: Nivetha, Narayanasamy, et al.
Publicado: (2022)

Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase
por: Altowyan, Mezna Saleh, et al.
Publicado: (2019)

Momilactones A and B Are α-Amylase and α-Glucosidase Inhibitors
por: Quan, Nguyen Van, et al.
Publicado: (2019)

Dietary Polyphenols as Natural Inhibitors of α-Amylase and α-Glucosidase
por: Ćorković, Ina, et al.
Publicado: (2022)

α-Glucosidase, α-Amylase and Antioxidant Evaluations of Isolated Bioactives from Wild Strawberry
por: Huneif, Mohammed A., et al.
Publicado: (2022)

In vitro α-amylase and α-glucosidase inhibitory effects and cytotoxic activity of Albizia antunesiana extracts
por: Chipiti, Talent, et al.
Publicado: (2015)

Defining the Role of Isoeugenol from Ocimum tenuiflorum against Diabetes Mellitus-Linked Alzheimer’s Disease through Network Pharmacology and Computational Methods
por: Martiz, Reshma Mary, et al.
Publicado: (2022)

Discovery of novel benzophenone integrated derivatives as anti-Alzheimer’s agents targeting presenilin-1 and presenilin-2 inhibition: A computational approach
por: Martiz, Reshma Mary, et al.
Publicado: (2022)

Post-prandial hyperglycemia
por: Singh, Santosh Kumar
Publicado: (2012)

Succinimide Derivatives as Antioxidant Anticholinesterases, Anti-α-Amylase, and Anti-α-Glucosidase: In Vitro and In Silico Approaches
por: Alshehri, Osama M., et al.
Publicado: (2022)

Synthesis and Evaluation of Coumarin-Chalcone Derivatives as α-Glucosidase Inhibitors
por: Hu, Chun-Mei, et al.
Publicado: (2022)

In vitro α-amylase and α-glucosidase Inhibitory and Cytotoxic Activities of Extracts from Cissus cornifolia Planch Parts
por: Chipiti, Talent, et al.
Publicado: (2017)

Inhibition of α-glucosidase, α-amylase, and aldose reductase by potato polyphenolic compounds
por: Kalita, Diganta, et al.
Publicado: (2018)

Synthesis and inhibitory activity of N-acetylpyrrolidine derivatives on α-glucosidase and α-amylase
por: Sansenya, Sompong, et al.
Publicado: (2020)

The α-Amylase and α-Glucosidase Inhibition Capacity of Grape Pomace: A Review
por: Cisneros-Yupanqui, Miluska, et al.
Publicado: (2022)

Influence of gallic acid on α-amylase and α-glucosidase inhibitory properties of acarbose
por: Oboh, Ganiyu, et al.
Publicado: (2016)

A Review of the In Vitro Inhibition of α-Amylase and α-Glucosidase by Chalcone Derivatives
por: Tran, Thanh-Dao, et al.
Publicado: (2023)

Modes of Inhibition of α-Amylase and α-Glucosidase by Aqueous Extract of Morinda lucida Benth Leaf
por: Kazeem, M. I., et al.
Publicado: (2013)

Postprandial Hyperglycemia Lowering Effect of the Isolated Compounds from Olive Mill Wastes – An Inhibitory Activity and Kinetics Studies on α-Glucosidase and α-Amylase Enzymes
por: Mwakalukwa, Rogers, et al.
Publicado: (2020)

Hypoglycemic Efficacy of Docking Selected Natural Compounds against α-Glucosidase and α-Amylase
por: Riyaphan, Jirawat, et al.
Publicado: (2018)

Synthesis of Benzylidene Analogs of Oleanolic Acid as Potential α-Glucosidase and α-Amylase Inhibitors
por: Ke, Jun-Jie, et al.
Publicado: (2022)

Responsive Fluorescent Coumarin–Cinnamic Acid Conjugates for α-Glucosidase Detection
por: Luo, Dong, et al.
Publicado: (2022)

Synthesis and Inhibitory Effect of Some Indole‐Pyrimidine Based Hybrid Heterocycles on α‐Glucosidase and α‐Amylase as Potential Hypoglycemic Agents
por: Badria, Farid A., et al.
Publicado: (2019)

Inhibition of α-Amylase, α-Glucosidase, and Lipase, Intestinal Glucose Absorption, and Antidiabetic Properties by Extracts of Erodium guttatum
por: Benrahou, Kaoutar, et al.
Publicado: (2022)

Development of an antidiabetic formulation (ADJ6) and its inhibitory activity against α-amylase and α-glucosidase
por: Duraiswamy, Anand, et al.
Publicado: (2015)

Assessment of Occupational Burnout among Intensive Care Unit Staff in Jazan, Saudi Arabia, Using the Maslach Burnout Inventory
por: Shbeer, Abdullah, et al.
Publicado: (2022)

Assessment of Professional Quality of Life Among Critical Care Nurses During the COVID-19 Pandemic in Saudi Arabia
por: Ageel, Mohammed, et al.
Publicado: (2022)

Assessment of the Critical Care Work Environment of Intensive Care Unit Nurses in Saudi Arabia
por: Ageel, Mohammed, et al.
Publicado: (2022)

Inhibition Kinetics and Theoretical Studies on Zanthoxylum chalybeum Engl. Dual Inhibitors of α-Glucosidase and α-Amylase
por: Kimani, Njogu M., et al.
Publicado: (2023)

In vitro α -amylase and α-glucosidase inhibitory potential of Trigonella foenum-graecum leaves extract
por: Ganeshpurkar, Aditya, et al.
Publicado: (2013)

In Vitro Inhibition of α-Amylase and α-Glucosidase by Extracts from Psiadia punctulata and Meriandra bengalensis
por: Kidane, Yosief, et al.
Publicado: (2018)

The α-amylase and α-glucosidase inhibitory activities of the dichloromethane extracts and constituents of Ferulago bracteata roots
por: Karakaya, Songül, et al.
Publicado: (2017)

Investigation into the Thermal Response and Pharmacological Activity of Substituted Schiff Bases on α-Amylase and α-Glucosidase
por: Okoli, Bamidele Joseph, et al.
Publicado: (2018)

Antioxidant, α-Amylase and α-Glucosidase Inhibitory Activities and Potential Constituents of Canarium tramdenum Bark
por: Quan, Nguyen Van, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_06atu4uar6vgp360qn2pm51214