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Antiviral Activities of HIV-1-Specific Human Broadly Neutralizing Antibodies Are Isotype-Dependent

Broadly neutralizing antibodies (bNAbs) offer promising opportunities for preventing HIV-1 infection. The protection mechanisms of bNAbs involve the Fc domain, as well as their Fab counterpart. Here, different bNAb isotypes including IgG1, IgA1, IgA2, and IgA122 (IgA2 with the hinge of IgA1) were ge...

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Detalles Bibliográficos
Autores principales:	Noailly, Blandine, Yaugel-Novoa, Melyssa, Werquin, Justine, Jospin, Fabienne, Drocourt, Daniel, Bourlet, Thomas, Rochereau, Nicolas, Paul, Stéphane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227833/ https://www.ncbi.nlm.nih.gov/pubmed/35746511 http://dx.doi.org/10.3390/vaccines10060903

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