Establishment of Level a In Vitro–In Vivo Correlation (IVIVC) via Extended DoE-IVIVC Model: A Donepezil Case Study

This study aimed to establish an extended design of experiment (DoE)-in vitro in vivo correlation (IVIVC) model that defines the relationship between formulation composition, in vitro dissolution, and in vivo pharmacokinetics. Fourteen sustained-release (SR) tablets of a model drug, donepezil, were...

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Detalles Bibliográficos
Autores principales: Lee, Da Young, Shin, Soyoung, Kim, Tae Hwan, Shin, Beom Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227873/
https://www.ncbi.nlm.nih.gov/pubmed/35745798
http://dx.doi.org/10.3390/pharmaceutics14061226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227873/
https://www.ncbi.nlm.nih.gov/pubmed/35745798
http://dx.doi.org/10.3390/pharmaceutics14061226

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