Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes

The development of oligonucleotide conjugates for in vivo targeting is one of the most exciting areas for oligonucleotide therapeutics. A major breakthrough in this field was the development of multifunctional GalNAc-oligonucleotides with high affinity to asialoglycoprotein receptors (ASGPR) that di...

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Detalles Bibliográficos
Autores principales: Clua, Anna, Grijalvo, Santiago, Erande, Namrata, Gupta, Swati, Yucius, Kristina, Gargallo, Raimundo, Mazzini, Stefania, Manoharan, Muthiah, Eritja, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228010/
https://www.ncbi.nlm.nih.gov/pubmed/35745067
http://dx.doi.org/10.3390/molecules27123944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228010/
https://www.ncbi.nlm.nih.gov/pubmed/35745067
http://dx.doi.org/10.3390/molecules27123944

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