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Mechanistic Insights into the Reaction of Amidines with 1,2,3-Triazines and 1,2,3,5-Tetrazines
[Image: see text] 1,2,3-Triazines and 1,2,3,5-tetrazines react rapidly, efficiently, and selectively with amidines to form pyrimidines/1,3,5-triazines, exhibiting an orthogonal reactivity with 1,2,4,5-tetrazine-based conjugation chemistry. Whereas the mechanism of the reaction of the isomeric 1,2,4-...
Autores principales: | Wu, Zhi-Chen, Houk, K. N., Boger, Dale L., Svatunek, Dennis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228069/ https://www.ncbi.nlm.nih.gov/pubmed/35666564 http://dx.doi.org/10.1021/jacs.2c03726 |
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