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Preoperative Phase Angle as a Risk Indicator in Cardiac Surgery—A Prospective Observational Study

Background: The phase angle (PhA) can be used for prognostic assessments in critically ill patients. This study describes the perioperative course of PhA and associated risk indicators in a cohort of elective cardiac surgical patients. Methods: The PhA was measured in 168 patients once daily until p...

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Autores principales: Ryz, Sylvia, Nixdorf, Larissa, Puchinger, Jürgen, Lassnigg, Andrea, Wiedemann, Dominik, Bernardi, Martin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228129/
https://www.ncbi.nlm.nih.gov/pubmed/35745221
http://dx.doi.org/10.3390/nu14122491
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author Ryz, Sylvia
Nixdorf, Larissa
Puchinger, Jürgen
Lassnigg, Andrea
Wiedemann, Dominik
Bernardi, Martin H.
author_facet Ryz, Sylvia
Nixdorf, Larissa
Puchinger, Jürgen
Lassnigg, Andrea
Wiedemann, Dominik
Bernardi, Martin H.
author_sort Ryz, Sylvia
collection PubMed
description Background: The phase angle (PhA) can be used for prognostic assessments in critically ill patients. This study describes the perioperative course of PhA and associated risk indicators in a cohort of elective cardiac surgical patients. Methods: The PhA was measured in 168 patients once daily until postoperative day (POD) seven. Patients were split into two groups depending on their median preoperative PhA and analyzed for several clinical outcomes; logistic regression models were used. Results: The PhA decreased from preoperative (6.1° ± 1.9°) to a nadir on POD 2 (3.5° ± 2.5°, mean difference −2.6° (95% CI, −3.0°; −2.1°; p < 0.0001)). Patients with lower preoperative PhA were older (71.0 ± 9.1 vs. 60.9 ± 12.0 years; p < 0.0001) and frailer (3.1 ± 1.3 vs. 2.3 ± 1.1; p < 0.0001), needed more fluids (8388 ± 3168 vs. 7417 ± 2459 mL, p = 0.0287), and stayed longer in the ICU (3.7 ± 4.5 vs. 2.6 ± 3.8 days, p = 0.0182). Preoperative PhA was independently influenced by frailty (OR 0.77; 95% CI 0.61; 0.98; p = 0.0344) and cardiac function (OR 1.85; 95%CI 1.07; 3.19; p = 0.028), whereas the postoperative PhA decline was independently influenced by higher fluid balances (OR 0.86; 95% CI 0.75; 0.99; p = 0.0371) and longer cardiopulmonary bypass times (OR 0.99; 95% CI 0.98; 0.99; p = 0.0344). Conclusion: Perioperative PhA measurement is an easy-to-use bedside method that may critically influence risk evaluation for the outcome of cardiac surgery patients.
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spelling pubmed-92281292022-06-25 Preoperative Phase Angle as a Risk Indicator in Cardiac Surgery—A Prospective Observational Study Ryz, Sylvia Nixdorf, Larissa Puchinger, Jürgen Lassnigg, Andrea Wiedemann, Dominik Bernardi, Martin H. Nutrients Article Background: The phase angle (PhA) can be used for prognostic assessments in critically ill patients. This study describes the perioperative course of PhA and associated risk indicators in a cohort of elective cardiac surgical patients. Methods: The PhA was measured in 168 patients once daily until postoperative day (POD) seven. Patients were split into two groups depending on their median preoperative PhA and analyzed for several clinical outcomes; logistic regression models were used. Results: The PhA decreased from preoperative (6.1° ± 1.9°) to a nadir on POD 2 (3.5° ± 2.5°, mean difference −2.6° (95% CI, −3.0°; −2.1°; p < 0.0001)). Patients with lower preoperative PhA were older (71.0 ± 9.1 vs. 60.9 ± 12.0 years; p < 0.0001) and frailer (3.1 ± 1.3 vs. 2.3 ± 1.1; p < 0.0001), needed more fluids (8388 ± 3168 vs. 7417 ± 2459 mL, p = 0.0287), and stayed longer in the ICU (3.7 ± 4.5 vs. 2.6 ± 3.8 days, p = 0.0182). Preoperative PhA was independently influenced by frailty (OR 0.77; 95% CI 0.61; 0.98; p = 0.0344) and cardiac function (OR 1.85; 95%CI 1.07; 3.19; p = 0.028), whereas the postoperative PhA decline was independently influenced by higher fluid balances (OR 0.86; 95% CI 0.75; 0.99; p = 0.0371) and longer cardiopulmonary bypass times (OR 0.99; 95% CI 0.98; 0.99; p = 0.0344). Conclusion: Perioperative PhA measurement is an easy-to-use bedside method that may critically influence risk evaluation for the outcome of cardiac surgery patients. MDPI 2022-06-16 /pmc/articles/PMC9228129/ /pubmed/35745221 http://dx.doi.org/10.3390/nu14122491 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ryz, Sylvia
Nixdorf, Larissa
Puchinger, Jürgen
Lassnigg, Andrea
Wiedemann, Dominik
Bernardi, Martin H.
Preoperative Phase Angle as a Risk Indicator in Cardiac Surgery—A Prospective Observational Study
title Preoperative Phase Angle as a Risk Indicator in Cardiac Surgery—A Prospective Observational Study
title_full Preoperative Phase Angle as a Risk Indicator in Cardiac Surgery—A Prospective Observational Study
title_fullStr Preoperative Phase Angle as a Risk Indicator in Cardiac Surgery—A Prospective Observational Study
title_full_unstemmed Preoperative Phase Angle as a Risk Indicator in Cardiac Surgery—A Prospective Observational Study
title_short Preoperative Phase Angle as a Risk Indicator in Cardiac Surgery—A Prospective Observational Study
title_sort preoperative phase angle as a risk indicator in cardiac surgery—a prospective observational study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228129/
https://www.ncbi.nlm.nih.gov/pubmed/35745221
http://dx.doi.org/10.3390/nu14122491
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