Cargando…

Trends in Influenza Infections in Three States of India from 2015–2021: Has There Been a Change during COVID-19 Pandemic?

The COVID-19 pandemic and public health response to the pandemic has caused huge setbacks in the management of other infectious diseases. In the present study, we aimed to (i) assess the trends in numbers of samples from patients with influenza-like illness and severe acute respiratory syndrome test...

Descripción completa

Detalles Bibliográficos
Autores principales: Jayaram, Anup, Jagadesh, Anitha, Kumar, Ajay M. V., Davtyan, Hayk, Thekkur, Pruthu, Vilas, Victor J. Del Rio, Mandal, Shrawan Kumar, Sudandiradas, Robin, Babu, Naren, Varamballi, Prasad, Shetty, Ujwal, Mukhopadhyay, Chiranjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228248/
https://www.ncbi.nlm.nih.gov/pubmed/35736988
http://dx.doi.org/10.3390/tropicalmed7060110
_version_ 1784734390724591616
author Jayaram, Anup
Jagadesh, Anitha
Kumar, Ajay M. V.
Davtyan, Hayk
Thekkur, Pruthu
Vilas, Victor J. Del Rio
Mandal, Shrawan Kumar
Sudandiradas, Robin
Babu, Naren
Varamballi, Prasad
Shetty, Ujwal
Mukhopadhyay, Chiranjay
author_facet Jayaram, Anup
Jagadesh, Anitha
Kumar, Ajay M. V.
Davtyan, Hayk
Thekkur, Pruthu
Vilas, Victor J. Del Rio
Mandal, Shrawan Kumar
Sudandiradas, Robin
Babu, Naren
Varamballi, Prasad
Shetty, Ujwal
Mukhopadhyay, Chiranjay
author_sort Jayaram, Anup
collection PubMed
description The COVID-19 pandemic and public health response to the pandemic has caused huge setbacks in the management of other infectious diseases. In the present study, we aimed to (i) assess the trends in numbers of samples from patients with influenza-like illness and severe acute respiratory syndrome tested for influenza and the number and proportion of cases detected from 2015–2021 and (ii) examine if there were changes during the COVID-19 period (2020–2021) compared to the pre-COVID-19 period (2015–2019) in three states of India. The median (IQR) number of samples tested per month during the pre-COVID-19 period was 653 (395–1245), compared to 27 (11–98) during the COVID-19 period (p value < 0.001). The median (IQR) number of influenza cases detected per month during the pre-COVID-19 period was 190 (113–372), compared to 29 (27–30) during the COVID-19 period (p value < 0.001). Interrupted time series analysis (adjusting for seasonality and testing charges) confirmed a significant reduction in the total number of samples tested and influenza cases detected during the COVID-19 period. However, there was no change in the influenza positivity rate between pre-COVID-19 (29%) and COVID-19 (30%) period. These findings suggest that COVID-19-related disruptions, poor health-seeking behavior, and overburdened health systems might have led to a reduction in reported influenza cases rather than a true reduction in disease transmission.
format Online
Article
Text
id pubmed-9228248
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-92282482022-06-25 Trends in Influenza Infections in Three States of India from 2015–2021: Has There Been a Change during COVID-19 Pandemic? Jayaram, Anup Jagadesh, Anitha Kumar, Ajay M. V. Davtyan, Hayk Thekkur, Pruthu Vilas, Victor J. Del Rio Mandal, Shrawan Kumar Sudandiradas, Robin Babu, Naren Varamballi, Prasad Shetty, Ujwal Mukhopadhyay, Chiranjay Trop Med Infect Dis Article The COVID-19 pandemic and public health response to the pandemic has caused huge setbacks in the management of other infectious diseases. In the present study, we aimed to (i) assess the trends in numbers of samples from patients with influenza-like illness and severe acute respiratory syndrome tested for influenza and the number and proportion of cases detected from 2015–2021 and (ii) examine if there were changes during the COVID-19 period (2020–2021) compared to the pre-COVID-19 period (2015–2019) in three states of India. The median (IQR) number of samples tested per month during the pre-COVID-19 period was 653 (395–1245), compared to 27 (11–98) during the COVID-19 period (p value < 0.001). The median (IQR) number of influenza cases detected per month during the pre-COVID-19 period was 190 (113–372), compared to 29 (27–30) during the COVID-19 period (p value < 0.001). Interrupted time series analysis (adjusting for seasonality and testing charges) confirmed a significant reduction in the total number of samples tested and influenza cases detected during the COVID-19 period. However, there was no change in the influenza positivity rate between pre-COVID-19 (29%) and COVID-19 (30%) period. These findings suggest that COVID-19-related disruptions, poor health-seeking behavior, and overburdened health systems might have led to a reduction in reported influenza cases rather than a true reduction in disease transmission. MDPI 2022-06-19 /pmc/articles/PMC9228248/ /pubmed/35736988 http://dx.doi.org/10.3390/tropicalmed7060110 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jayaram, Anup
Jagadesh, Anitha
Kumar, Ajay M. V.
Davtyan, Hayk
Thekkur, Pruthu
Vilas, Victor J. Del Rio
Mandal, Shrawan Kumar
Sudandiradas, Robin
Babu, Naren
Varamballi, Prasad
Shetty, Ujwal
Mukhopadhyay, Chiranjay
Trends in Influenza Infections in Three States of India from 2015–2021: Has There Been a Change during COVID-19 Pandemic?
title Trends in Influenza Infections in Three States of India from 2015–2021: Has There Been a Change during COVID-19 Pandemic?
title_full Trends in Influenza Infections in Three States of India from 2015–2021: Has There Been a Change during COVID-19 Pandemic?
title_fullStr Trends in Influenza Infections in Three States of India from 2015–2021: Has There Been a Change during COVID-19 Pandemic?
title_full_unstemmed Trends in Influenza Infections in Three States of India from 2015–2021: Has There Been a Change during COVID-19 Pandemic?
title_short Trends in Influenza Infections in Three States of India from 2015–2021: Has There Been a Change during COVID-19 Pandemic?
title_sort trends in influenza infections in three states of india from 2015–2021: has there been a change during covid-19 pandemic?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228248/
https://www.ncbi.nlm.nih.gov/pubmed/35736988
http://dx.doi.org/10.3390/tropicalmed7060110
work_keys_str_mv AT jayaramanup trendsininfluenzainfectionsinthreestatesofindiafrom20152021hastherebeenachangeduringcovid19pandemic
AT jagadeshanitha trendsininfluenzainfectionsinthreestatesofindiafrom20152021hastherebeenachangeduringcovid19pandemic
AT kumarajaymv trendsininfluenzainfectionsinthreestatesofindiafrom20152021hastherebeenachangeduringcovid19pandemic
AT davtyanhayk trendsininfluenzainfectionsinthreestatesofindiafrom20152021hastherebeenachangeduringcovid19pandemic
AT thekkurpruthu trendsininfluenzainfectionsinthreestatesofindiafrom20152021hastherebeenachangeduringcovid19pandemic
AT vilasvictorjdelrio trendsininfluenzainfectionsinthreestatesofindiafrom20152021hastherebeenachangeduringcovid19pandemic
AT mandalshrawankumar trendsininfluenzainfectionsinthreestatesofindiafrom20152021hastherebeenachangeduringcovid19pandemic
AT sudandiradasrobin trendsininfluenzainfectionsinthreestatesofindiafrom20152021hastherebeenachangeduringcovid19pandemic
AT babunaren trendsininfluenzainfectionsinthreestatesofindiafrom20152021hastherebeenachangeduringcovid19pandemic
AT varamballiprasad trendsininfluenzainfectionsinthreestatesofindiafrom20152021hastherebeenachangeduringcovid19pandemic
AT shettyujwal trendsininfluenzainfectionsinthreestatesofindiafrom20152021hastherebeenachangeduringcovid19pandemic
AT mukhopadhyaychiranjay trendsininfluenzainfectionsinthreestatesofindiafrom20152021hastherebeenachangeduringcovid19pandemic