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In-Depth Characterization of a Re-Engineered Cholera Toxin Manufacturing Process Using Growth-Decoupled Production in Escherichia coli

Non-toxic derivatives of the cholera toxin are extensively used in neuroscience, as neuronal tracers to reveal the location of cells in the central nervous system. They are, also, being developed as vaccine components and drug-delivery vehicles. Production of cholera-toxin derivatives is often non-r...

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Detalles Bibliográficos
Autores principales: Danielewicz, Natalia, Dai, Wenyue, Rosato, Francesca, Webb, Michael E., Striedner, Gerald, Römer, Winfried, Turnbull, W. Bruce, Mairhofer, Juergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228256/
https://www.ncbi.nlm.nih.gov/pubmed/35737057
http://dx.doi.org/10.3390/toxins14060396