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In Silico Antiprotozoal Evaluation of 1,4-Naphthoquinone Derivatives against Chagas and Leishmaniasis Diseases Using QSAR, Molecular Docking, and ADME Approaches

Chagas and leishmaniasis are two neglected diseases considered as public health problems worldwide, for which there is no effective, low-cost, and low-toxicity treatment for the host. Naphthoquinones are ligands with redox properties involved in oxidative biological processes with a wide variety of...

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Detalles Bibliográficos
Autores principales: Prieto Cárdenas, Lina S., Arias Soler, Karen A., Nossa González, Diana L., Rozo Núñez, Wilson E., Cárdenas-Chaparro, Agobardo, Duchowicz, Pablo R., Gómez Castaño, Jovanny A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228275/
https://www.ncbi.nlm.nih.gov/pubmed/35745607
http://dx.doi.org/10.3390/ph15060687