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Catalytic Properties of Caseinolytic Protease Subunit of Plasmodium knowlesi and Its Inhibition by a Member of δ-Lactone, Hyptolide

The caseinolytic protease (Clp) system plays an essential role in the protein homeostasis of the malaria parasite, particularly at the stage of apicoplast development. The inhibition of this protein is known to have a lethal effect on the parasite and is therefore considered an interesting avenue fo...

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Detalles Bibliográficos
Autores principales: Budiman, Cahyo, Razak, Raimalynah Abd, Unggit, Angelesa Runin Anak, Razali, Rafida, Suzery, Meiny, Mokhtar, Ruzaidi Azli Mohd, Lee, Ping-Chin, Utomo, Didik Huswo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228282/
https://www.ncbi.nlm.nih.gov/pubmed/35744912
http://dx.doi.org/10.3390/molecules27123787