Cargando…
Chimeric Antigen by the Fusion of SARS-CoV-2 Receptor Binding Domain with the Extracellular Domain of Human CD154: A Promising Improved Vaccine Candidate
COVID-19 is a respiratory viral disease caused by a new coronavirus called SARS-CoV-2. This disease has spread rapidly worldwide with a high rate of morbidity and mortality. The receptor-binding domain (RBD) of protein spike (S) mediates the attachment of the virus to the host’s cellular receptor. T...
Autores principales: | Ávalos, Ileanet, Lao, Thailin, Rodríguez, Elsa María, Zamora, Yasser, Rodríguez, Alianet, Ramón, Ailyn, Lemos, Gilda, Cabrales, Ania, Bequet-Romero, Monica, Casillas, Dionne, Andújar, Ivan, Espinosa, Luis Ariel, González, Luis Javier, Alvarez, Yanitza, Carpio, Yamila, Estrada, Mario Pablo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228316/ https://www.ncbi.nlm.nih.gov/pubmed/35746505 http://dx.doi.org/10.3390/vaccines10060897 |
Ejemplares similares
-
Production and characterization of a chimeric antigen, based on nucleocapsid of SARS-CoV-2 fused to the extracellular domain of human CD154 in HEK-293 cells as a vaccine candidate against COVID-19
por: Lao, Thailin, et al.
Publicado: (2023) -
Transient Expression in HEK-293 Cells in Suspension Culture as a Rapid and Powerful Tool: SARS-CoV-2 N and Chimeric SARS-CoV-2N-CD154 Proteins as a Case Study
por: Lao, Thailin, et al.
Publicado: (2023) -
A recombinant SARS-CoV-2 receptor-binding domain expressed in an engineered fungal strain of Thermothelomyces heterothallica induces a functional immune response in mice
por: Lazo, Laura, et al.
Publicado: (2022) -
An engineered SARS-CoV-2 receptor-binding domain produced in Pichia pastoris as a candidate vaccine antigen
por: Limonta-Fernández, Miladys, et al.
Publicado: (2022) -
Requirement of Transmembrane Domain for CD154 Association to Lipid Rafts and Subsequent Biological Events
por: Benslimane, Nadir, et al.
Publicado: (2012)