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Polyamine Depletion Strategies in Cancer: Remodeling the Tumor Immune Microenvironment to Enhance Anti-Tumor Responses

Polyamine biosynthesis is frequently dysregulated in cancers, and enhanced flux increases intracellular polyamines necessary for promoting cell growth, proliferation, and function. Polyamine depletion strategies demonstrate efficacy in reducing tumor growth and increasing survival in animal models o...

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Detalles Bibliográficos
Autores principales:	Chin, Alexander, Bieberich, Charles J., Stewart, Tracy Murray, Casero, Robert A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228337/ https://www.ncbi.nlm.nih.gov/pubmed/35736351 http://dx.doi.org/10.3390/medsci10020031

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