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The Phospholipase Activity of Ammodytoxin, a Prototype Snake Venom β-Neurotoxin, Is Not Obligatory for Cell Internalisation and Translocation to Mitochondria
β-Neurotoxins are secreted phospholipase A(2) molecules that inhibit transmission in neuromuscular synapses by poisoning the motor neurons. These toxins specifically and rapidly internalise into the nerve endings of motor neurons. Ammodytoxin (Atx) is a prototype β-neurotoxin from the venom of the n...
Autores principales: | Ivanušec, Adrijan, Šribar, Jernej, Veranič, Peter, Križaj, Igor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228470/ https://www.ncbi.nlm.nih.gov/pubmed/35737036 http://dx.doi.org/10.3390/toxins14060375 |
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